763062-17-5Relevant academic research and scientific papers
The discovery of YM-60828: a potent, selective and orally-bioavailable factor Xa inhibitor.
Hirayama, Fukushi,Koshio, Hiroyuki,Katayama, Naoko,Kurihara, Hiroyuki,Taniuchi, Yuta,Sato, Kazuo,Hisamichi, Nami,Sakai-Moritani, Yumiko,Kawasaki, Tomihisa,Matsumoto, Yuzo,Yanagisawa, Isao
, p. 1509 - 1523 (2007/10/03)
Since Factor Xa (FXa) is well known to play a central role in thrombosis and hemostasis, inhibition of FXa is an attractive target for antithrombotic strategies. As a part of our investigation of a non-peptide, orally available FXa inhibitor, we found tha
