76318-50-8

Basic information

• Product Name: METHYL 3,5-DIIODO-L-TYROSINATE
• Synonyms: L-TYROSINE, 3,5-DIIODO-, METHYL ESTER;METHYL 3,5-DIIODO-L-TYROSINATE;3,5-DIIODO-L-TYROSINE METHYL ESTER;Methyl 3,5-diiodo-L-tyrosinate 98%;(S)-Methyl 2-aMino-3-(4-hydroxy-3,5-diiodophenyl)propanoate
• CAS NO: 76318-50-8
• Molecular Formula: C₁₀H₁₁I₂NO₃
• Molecular Weight: 447.01
• Product Categories: Chiral Compound
• Mol File: 76318-50-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 373.6oC at 760 mmHg
• Flash Point: 179.8oC
• Appearance: /
• Density: 2.176g/cm3
• Vapor Pressure: 4.11E-06mmHg at 25°C
• Refractive Index: 1.684
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 3,5-DIIODO-L-TYROSINATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3,5-DIIODO-L-TYROSINATE(76318-50-8)
• EPA Substance Registry System: METHYL 3,5-DIIODO-L-TYROSINATE(76318-50-8)

Safety Data

• Hazardous Substances Data: 76318-50-8(Hazardous Substances Data)

Usage

General Description

Methyl 3,5-diiodo-L-tyrosinate is a chemical compound containing the methyl ester of 3,5-diiodo-L-tyrosine. It is primarily used as an intermediate in the synthesis of pharmaceuticals and research chemicals. METHYL 3,5-DIIODO-L-TYROSINATE has potential applications in medical research and drug discovery due to its ability to modulate biological processes and serve as a building block for more complex molecules. Its unique structure and functional groups make it a valuable component in the development of new drugs and treatments. However, it is important to handle this compound with caution and adhere to proper safety protocols due to its potential reactivity and toxicity.

InChI:InChI=1/C10H11I2NO3/c1-16-10(15)8(13)4-5-2-6(11)9(14)7(12)3-5/h2-3,8,14H,4,13H2,1H3/t8-/m1/s1

Upstream product

• 60-18-4 L-tyrosine 
• 67-56-1 methanol 
• 300-39-0 3,5-diiodo-l-tyrosine 
• 1080-06-4 L-Tyr-OMe 

Downstream Products

• 128781-80-6 (S)-methyl 2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3,5-diiodophenyl)propanoate 
• 123418-40-6 (9S,12S,15S)-9-Acetylamino-12-(4-benzyloxy-benzyl)-5-chloro-4-hydroxy-19,20-diiodo-10,13-dioxo-2-oxa-11,14-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3,5,7⁽²²⁾,17⁽²¹⁾,18-hexaene-15-carboxylic acid methyl ester 
• 123418-39-3 (9S,12S,15S)-15-Acetylamino-12-(4-benzyloxy-benzyl)-19,20-dichloro-4-hydroxy-5-iodo-11,14-dioxo-2-oxa-10,13-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3⁽²²⁾,4,6,17⁽²¹⁾,18-hexaene-9-carboxylic acid methyl ester 
• 123418-38-2 N-acetyl-3,5-dichloro-L-tyrosyl-O-benzyl-L-tyrosyl-3,5-diiodo-L-tyrosinemethyl ester 
• 123418-37-1 (S)-2-[(S)-2-Amino-3-(4-benzyloxy-phenyl)-propionylamino]-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid methyl ester; hydrochloride 
• 123418-35-9 (9S,12S,15S)-9-Acetylamino-4-hydroxy-12-(4-hydroxy-benzyl)-10,13-dioxo-2-oxa-11,14-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3,5,7⁽²²⁾,17⁽²¹⁾,18-hexaene-15-carboxylic acid methyl ester 
• 123418-36-0 (9S,12S,15S)-9-Acetylamino-4-hydroxy-12-(4-hydroxy-benzyl)-10,13-dioxo-2-oxa-11,14-diaza-tricyclo[15.2.2.1^3,7]docosa-1⁽²⁰⁾,3,5,7⁽²²⁾,17⁽²¹⁾,18-hexaene-15-carboxylic acid 
• 120363-27-1 Methyl (9S,12S,15S)-15-(acetylamino)-4-hydroxy-12-<(4-hydroxyphenyl)methyl>-11,14-dioxo-2-oxa-10,13-diazatricyclo<15.2.2.1^3,7>docosa-3,5,7(22),17,19,20-hexaene-9-carboxylate 
• 108890-90-0 K-13 
• 95253-83-1 3.5-diiodo-N-(N-benzyloxycarbonyl-α-L-glutamyl)-L-tyrosine 
• 56460-41-4 3.5-diiodo-N-acetyl-L-tyrosine methyl ester 

Relevant articles and documents

COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF

Provided are a compound including a cleavable linker, a use thereof, and an intermediate compound for preparing the same, and more particularly, the compound including a cleavable linker of the present invention may include an active agent (for example, a drug, a toxin, a ligand, a probe for detection, etc.) having a specific function or activity, a SO2 functional group which is capable of selectively releasing the active agent, and a functional group which triggers a chemical reaction, a physicochemical reaction and/or a biological reaction by external stimulation, and may further include a ligand (for example, oligopeptide, polypeptide, antibody, etc.) having binding specificity for a desired target receptor.

Tyrosine-derived stimuli responsive, fluorescent amino acids

A series of fluorescent unnatural amino acids (UAAs) bearing stilbene and meta-phenylenevinylene (m-PPV) backbone have been synthesized and their optical properties were studied. These novel UAAs were derived from protected diiodo-l-tyrosine using palladi