76345-27-2Relevant academic research and scientific papers
Electrochemical Synthesis of Carbodiimides via Metal/Oxidant-Free Oxidative Cross-Coupling of Amines and Isocyanides
Badsara, Satpal Singh,Jaiswal, Pradeep K.,Malviya, Bhanwar Kumar,Sharma, Siddharth,Verma, Ved Prakash
supporting information, (2020/03/19)
This work discloses an electrochemical oxidative cross-coupling of amines with aryl and aliphatic isocyanides. In an undivided cell, the reaction proceeds without involving any transition-metal catalyst, oxidant, or toxic reagents providing carbodiimides in good yields, thereby circumventing stoichiometric chemical oxidants, with H2 as the only byproduct. Moreover, carbodiimides were in situ converted into unsymmetrical ureas in moderate to good yields using an electricity ON-OFF strategy.
Ultrasonic-assisted synthesis of carbodiimides from N,N′-disubstituted thioureas and ureas
Duangkamol, Chuthamat,Pattarawarapan, Mookda,Phakhodee, Wong
, p. 1945 - 1949 (2016/10/21)
A facile and efficient sonochemical method for the preparation of carbodiimides from their corresponding thioureas or ureas was described. Using Ph3P–I2 combination in the presence of triethylamine, various diaryl, aryl–alkyl, as well as dialkyl substituted substrates could be converted into carbodiimides in good-to-excellent yields within short reaction times under mild conditions with simple experimental setup. Graphical abstract: [Figure not available: see fulltext.]
Ultrasound-assisted synthesis of substituted guanidines from thioureas
Pattarawarapan, Mookda,Jaita, Subin,Wangngae, Sirilak,Phakhodee, Wong
supporting information, p. 1354 - 1358 (2018/03/29)
Ultrasound-assisted synthesis of guanidine derivatives was developed using 2,4,6-trichloro-1,3,5-triazine as an inexpensive dehydrosulfurization reagent. Both 1,3-alkylaryl- and 1,3-diaryl-thioureas were rapidly converted into carbodiimides before subsequent reaction with aromatic or aliphatic amines. The method allows rapid access to highly substituted guanidines in good to excellent yields under mild conditions and with minimal use of solvent.
N,N-Dialkylcarbodiimide synthesis by palladium-catalysed coupling of amines with isonitriles
Pri-Bar, Ilan,Schwartz, Jeffrey
, p. 347 - 348 (2007/10/03)
Catalytic condensation of amines and isonitriles can be accomplished efficiently at 100°C using a palladium complex catalyst, oxygen, and iodine to give N,N-dialkylcarbodiimides.
