76345-70-5

Upstream product

• 25917-87-7 4-amino-3-nitrophenylcarbamic acid ethyl ester 
• 5131-58-8 2,4-diaminonitrobenzene 
• 945535-02-4 (3-amino-4-nitro-phenyl)-carbamic acid ethyl ester 
• 5307-14-2 2-nitro-1,4-phenylenediamine 

Downstream Products

• 1021160-64-4 [2-(2-chloro-phenyl)-3H-benzoimidazol-5-yl]-carbamic acid ethyl ester 
• 76345-71-6 2-phenylbenzimidazole-5-carbamic acid ethyl ester hydrochloride 

Relevant academic research and scientific papers

ORGANIC COMPOUNDS

The present invention provides compounds of the following structure; [in-line-formulae]A-L1-B-C-D[/in-line-formulae] that are useful for treating or preventing conditions or disorders associated with DGAT1 activity in animals, particularly humans.

METHOD OF TREATMENT

Method of of preventing or treating myocardial ischemia by inhibiting DGAT1 enzyme with a DGAT1 inhibitor compound.

Selective Functionalization in 2-Nitro-p-phenylenediamine : Part I - Synthesis of Derivatives of 5-Aminobenzimidazole

2-Nitro-p-phenylenediamine (3) reacts with several electrophilic reagents selectively on the amine meta to the nitro group.The products (4) can be reduced catalytically to the diamines (5) and then cyclized by means of N-carbalkoxy-S-methylpseudothiourea