76390-64-2

Basic information

• Product Name: 3-Isoxazolecarboxamide, 4-amino-5-benzoyl-
• Synonyms: 4-amino-5-benzoylisoxazole-3-carboxamide;4-Amino-5-benzoylisoxazol-3-carboxamid;HMS1384E03;4-amino-5-benzoylisoxazolo-3-carboxamide
• CAS NO: 76390-64-2
• Molecular Formula: C11H9N3O3
• Molecular Weight: 231.20700
• Mol File: 76390-64-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-Isoxazolecarboxamide, 4-amino-5-benzoyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolecarboxamide, 4-amino-5-benzoyl-(76390-64-2)
• EPA Substance Registry System: 3-Isoxazolecarboxamide, 4-amino-5-benzoyl-(76390-64-2)

Safety Data

• Hazardous Substances Data: 76390-64-2(Hazardous Substances Data)

Usage

Chemical compound

3-Isoxazolecarboxamide, 4-amino-5-benzoyl-

Potential application

pharmaceuticals

Derivative

isoxazolecarboxamide with benzoyl group attached to amino group
Candidate for drug development

Studied for biological activities

anti-inflammatory and analgesic properties
Investigated for potential use in treatment of various diseases and conditions
Valuable building block for synthesis of new compounds with therapeutic potential

Upstream product

• 57967-31-4 Cyan(phenacyloxyimino)acetamid 
• 76390-68-6 4-Amino-5-benzoylisoxazol-3-carbonitril 
• 70-11-1 α-bromoacetophenone 
• 100-46-9 benzylamine 
• 76390-52-8 α-cyano-α-phenacyloxyiminoacetamide 

Downstream Products

• 159850-74-5 3-benzoyl-5-phenyl-7-oxo-6,7-dihydroisoxazolo<4,3-d>pyrimidine 
• 165611-09-6 4-Amino-5-{[(E)-hydroxyimino]-phenyl-methyl}-isoxazole-3-carboxylic acid amide 
• 1271740-62-5 C₁₃H₁₀N₄O₃ 
• 1236197-34-4 5-methyl-7-phenyl-isoxazolo[4,5-d]pyrimidine-3-carboxamide 
• 165611-01-8 3-carbamido-5-chloromethyl-7-phenylisoxazolo<4,5-d>pyrimidine 
• 1093747-66-0 4-amino-5-benzoylisoxazole-3-carbohydrazide 
• 159850-78-9 3-benzoyl-6-benzyl-6,7-dihydroisoxazolo<4,3-d>pyrimidin-7-one 
• 159850-79-0 3-benzoyl-5-chloromethyl-7-oxo-6,7-dihydroisoxazolo<4,3-d>pyrimidine 

Relevant articles and documents

Synthesis of isoxazolo[4,5-e][1,4]diazepin-5-ones from 5-acyl-4- (haloacetylamino)isoxazoles

Treatment of 5-benzoyl-4-(iodoacetylamino)isoxazoles with alcoholic ammonia leads to isoxazolo[4,5-e][1,4]diazepin-5-ones, whereas the analogous chloroacetylamino derivatives are converted into a mixture of the deacylated 4-aminoisoxazoles and isoxazolo- [4,5-d]pyrimidines.

Synthesis and pharmacological properties of derivatives of isoxazolo[4,3-d]pyrimidine. III

Synthesis of new isoxazole[4,5-d]pyrimidine derivatives is reported. Some of isoxazolo[4,5-d]pyrimidine derivatives were tested for anticonvulsant, anxiolytic and antiserotonine activity. Compounds 14 and 16 proved active against hypothermia induced by re