76390-68-6

Upstream product

• 76390-55-1 (Phenacyloxyimino)malonsaeuredinitril 
• 57967-31-4 Cyan(phenacyloxyimino)acetamid 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 76390-64-2 4-amino-5-benzoylisoxazole-3-carboxamide 

Relevant academic research and scientific papers

Synthesis and pharmacological properties of derivatives of isoxazolo[4,3-d]pyrimidine. III

Synthesis of new isoxazole[4,5-d]pyrimidine derivatives is reported. Some of isoxazolo[4,5-d]pyrimidine derivatives were tested for anticonvulsant, anxiolytic and antiserotonine activity. Compounds 14 and 16 proved active against hypothermia induced by re

4-Aminoisoxazoles by Thorpe Cyclization

Cyclization of α-(acylmethoxyimino)nitriles 1 in the presence of lithium hydroxide yields 5-acyl-4-aminoisoxazoles 2.Compounds 2f and 2a can be converted into the isoxazolopyrimidone 3 and the isoxazolopyridine 4.