76393-16-3

Usage

Uses

Used in Pharmaceutical Industry:
ETHYL 2-ISOCYANATOBENZOATE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a versatile building block in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Pesticide Industry:
In the agricultural sector, ETHYL 2-ISOCYANATOBENZOATE is utilized as a component in the production of pesticides. Its incorporation aids in the creation of effective pest control agents, thereby supporting crop protection and ensuring food security.
Used in Chemical Product Industry:
ETHYL 2-ISOCYANATOBENZOATE also finds application in the broader chemical product industry, where it is employed in the manufacturing process of a range of chemical products. Its versatility and reactivity make it a valuable component in various chemical formulations and industrial applications.

InChI:InChI=1/C10H9NO3/c1-2-14-10(13)8-5-3-4-6-9(8)11-7-12/h3-6H,2H2,1H3

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 179240-09-6 (3aR,9bR)-2-aminoethyl-6-methoxy-2,3,3a,4,5,9b-[1H]-hexahydrobenz[e]isoindole 
• 87-25-2 2-ethoxycarbonylaniline 
• 75-44-5 phosgene 
• 130399-61-0 ethyl N-(trimethylsilyl)anthranilate 

Downstream Products

• 94814-88-7 N-(Phthalimidoyl-oxycarbonyl)-anthranilsaeureethylester 
• 114559-88-5 2-[3-((1R,3R,5S)-8-Methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-ureido]-benzoic acid ethyl ester 
• 94814-89-8 N-(o-Ethoxycarbonyl-phenyl)-N'-butyl-harnstoff 
• 72368-50-4 ethyl 2-(formylamino) benzoate 
• 35472-56-1 N-methyl-anthranilic acid ethyl ester 
• 29055-08-1 N-methyl-o-aminobenzyl alcohol 
• 1002339-47-0 tert-butyl 4-{[2-(ethoxycarbonyl)phenyl]carbamoyl}-3-(hydroxymethyl)piperazine-1-carboxylate 
• 76393-22-1 2-amino-3-nitro-5-(trifluoromethyl)-2'-(ethoxycarbonyl)carbanilide 
• 124420-83-3 2-[3-(pyridin-4-yl)-ureido]-benzoic acid 
• 221167-05-1 ethyl 3-ethoxy-7-[4-((2-ethoxycarbonylphenylamino)carbonyloxymethyl)imidazol-1-yl]-6-nitroquinoxaline-2-carboxylate 
• 124420-84-4 2-(3-Pyridin-4-yl-ureido)-benzoic acid ethyl ester 

Relevant academic research and scientific papers

Organosilicon synthesis of isocyanates: III. Synthesis of aliphatic, carbocyclic, aromatic, and alkylaromatic isocyanatocatboxylic acid esters

A series of aminoacid esters was prepared by treating the aminoacid suspensions in ethanol with thionyl chloride. Best conversion of aminoacid esters to corresponding isocyanates was achieved in the case of aromatic and carbocyclic aminoesters by phosgeneation of their N-silyl derivatives, and in the case of aliphatic and alkylaromatic aminoesters by phosgeneation of O-silyl or N,O-bissilylurethanes on their basis. In the last case additional step of esterification of the by-products isocyanatoalkylcarboxylic acid chlorides is required after phosgeneation. Unusual generation of cynnamates and intramolecular N→O-migration of trimethylsilyl group in the solutions of silylated alkylaromatic β-aminoacid esters were found. Pleiades Publishing, Inc., 2006.

Bicyclic substituted hexahydrobenz ?e! isoindole alpha-1 adrenergic antagonists

The present invention relates to a compound of the formula STR1 and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are α-1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are α-1 antagonist compositions and a method for antagonizing α-1 receptors and treating BPH.

BICYCLIC SUBSTITUTED HEXAHYDROBENZ[E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS

The present invention relates to a compound of the formula STR1 and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are α-1 adrenergic antagonists and are useful in the treatment of BPH; also d

5-Hydroxytryptamine (5-HT3) Receptor Antagonists. 3. Ortho-Substituted Phenylureas

A novel series of potent 5-HT3 receptor antagonists, ortho-substituted phenylureas 6a-z, is described in which the 5-membered ring of the previously reported indazoles and indolines has been replaced by an intramolecular hydrogen bond.High potency was found both for carbamate 6a and urea 6b.Granatane 6c was less potent than the equivalent tropane.Phenylurea 11c lacking the ortho substituent was inactive.Whereas further substitution could not be tolerated in the aromatic ring, activity was retained with a range of O-alkyl groups, compounds 6k-t.In addition, good activity was found for ortho ester 6u and sulfonamide 6x.The ortho-substituted phenylureas can therefore be regarded as bioisosteres of the 6,5-heterocycles indole, indazole, and indoline.