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7-Bromo-5-chloro-8-hydroxyquinoline is an organobromine compound that also contains chlorine. It is a multi-substituted quinoline derivative, consisting of a benzene ring fused to a pyridine ring. The benzene ring has a bromo and a hydroxy substituent at the 7th and 8th positions, respectively, while the pyridine ring has a chloro substituent at the 5th position. This chemical, due to its structure, possesses potential medicinal properties and can be utilized for the synthesis of complex pharmaceuticals. It serves as a versatile intermediate in the synthesis of various pharmaceutical agents, thanks to the active functional groups present in its structure.

7640-33-7

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7640-33-7 Usage

Uses

Used in Pharmaceutical Research:
7-Bromo-5-chloro-8-hydroxyquinoline is used as a versatile intermediate for the synthesis of complex pharmaceuticals, due to its active functional groups and potential medicinal properties.
Used in Academic Research:
7-BROMO-5-CHLORO-8-HYDROXYQUINOLINE is also utilized in academic research, where it can be studied for its chemical properties and potential applications in the development of new drugs and pharmaceutical agents.

Check Digit Verification of cas no

The CAS Registry Mumber 7640-33-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,4 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7640-33:
(6*7)+(5*6)+(4*4)+(3*0)+(2*3)+(1*3)=97
97 % 10 = 7
So 7640-33-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H5BrClNO/c10-6-4-7(11)5-2-1-3-12-8(5)9(6)13/h1-4,13H

7640-33-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Bromo-5-chloro-8-hydroxyquinoline

1.2 Other means of identification

Product number -
Other names 7-bromo-5-chloroquinolin-8-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:7640-33-7 SDS

7640-33-7Downstream Products

7640-33-7Relevant academic research and scientific papers

Study on Relationship Between Fluorescence Properties and Structure of Substituted 8-Hydroxyquinoline Zinc Complexes

Jianbo, He,Tingting, Zhou,Yongjing, Cao,Yuanyuan, Zhang,Weiqing, Yang,Menglin, Ma

, p. 1121 - 1126 (2018/08/17)

Organic light-emitting diodes (OLEDs) produced from 8-hydroxyquinoline metal complexes play a vital role in modern electroluminescent devices. In this manuscript, a series of 8-hydroxyquinoline derivatives were synthesized by different methods and their corresponding zinc metal complexes were prepared. The UV and fluorescence properties of the complexes were measured aiming to understand the effect of substituents at the quinoline ring on the fluorescence properties of the complexes. When the C-5 of 8-hydroxyquinoline was replaced by halogen group, the fluorescence emission wavelengths had been red-shifted, at the same time, blue-shifted of fluorescence emission wavelength was observed when the C-5 position of 8-hydroxyquinoline was substituted by electron-withdrawing group. When the C-4 position of 8-hydroxyquinolie was substituted by methyl or the C-5 position was substituted by sulfonic acid group, the corresponding zinc complexes had higher fluorescence intensity than 8-hydroxyquinolie zinc.

Bromine-Lithium Exchange on Bromo-8-hydroxyquinolines via Formation of their Sodium Salts.

Mongin, Florence,Fourquez, Jean-Marie,Rault, Stephanie,Levacher, Vincent,Godard, Alain,et al.

, p. 8415 - 8418 (2007/10/02)

A short and versatile method is reported for the preparation of 8-hydroxyquinoline derivatives by reaction of n-butyllithium with 5,7-dibromo-8-hydroxyquinoline 2 and 7-bromo-8-hydroxyquinoline 1 as their sodium salts.Thus, bromine-lithium exchange reaction on compound 2, highly regioselective, gave after addition of various electrophiles, 5-substituted 7-bromo-8-hydroxyquinolines 4a-j in moderate to good yields.The same procedure was also applicable to 7-bromo-8-hydroxyquinoline 1 which led to 7-substituted 8-hydroxyquinolines 3a-b.

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