76400-16-3

Upstream product

• 143869-96-9 (S)-1-((S)-3-Benzyloxycarbonylamino-2-tert-butoxycarbonylamino-propionyl)-pyrrolidine-2-carboxylic acid methyl ester 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 65710-57-8 3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine 

Downstream Products

• 76400-17-4 N-α-(1-Carboxy-3-Phenylpropyl)-β-amino-D,L-alanyl-L-proline 
• 143870-08-0 C₄₁H₆₃N₇O₁₁SSi 
• 143869-97-0 (S)-1-((S)-3-Benzyloxycarbonylamino-2-formylamino-propionyl)-pyrrolidine-2-carboxylic acid 

Relevant academic research and scientific papers

An approach toward the total synthesis of cyclotheonamides; preparation of a C(1) to N(14) segment

The C(1) to N(14) segment of the potent thrombin inhibitor cyclotheonamide A was prepared from L-arginine, L-proline, and L-asparagine. The arginine backbone was extended via a cyanohydrin, and the usual diaminopropanoic acid residue was obtained from hypervalent iodine oxidation of the asparagine side chain.