76411-80-8 Usage
Uses
Used in Pharmaceutical Research:
(S)-MPMP is used as a biochemical research tool for studying the effects of GABA receptors in the central nervous system, aiding in the understanding of their role in anxiety and related disorders.
Used in Medication Development:
(S)-MPMP is used as a potential candidate for the development of new medications for the treatment of anxiety and related disorders, due to its sedative and anxiolytic effects.
Used in Organic Synthesis:
(S)-MPMP is used as a catalyst in organic synthesis, contributing to the efficiency and selectivity of chemical reactions.
Used in Pharmaceutical Precursor Development:
(S)-MPMP is used as a precursor in the development of new pharmaceuticals, providing a foundation for the creation of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 76411-80-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,4,1 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 76411-80:
(7*7)+(6*6)+(5*4)+(4*1)+(3*1)+(2*8)+(1*0)=128
128 % 10 = 8
So 76411-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H20N2/c1-11-6-4-5-10(11)9-12-7-2-3-8-12/h10H,2-9H2,1H3/t10-/m1/s1
76411-80-8Relevant academic research and scientific papers
Synthesis of chiral diamines using novel 2-trichloromethyloxazolidin-4-one precursors derived from 5-oxo-proline and proline
Amedjkouh, Mohamed,Ahlberg, Per
, p. 2229 - 2234 (2007/10/03)
Efficient syntheses of chiral vicinal diamines derived from (S)-oxo-proline and (S)-proline are described. The novel diastereomerically pure precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo-[3.3.0]-octan-4,8-dione 3 and its enantiomer are readily available by reaction of the inexpensive enantiomers of 5-oxo-proline with chloral. Compound 3 reacts with primary and secondary amines to afford the 5-oxo-prolylamides 4 in quantitative yield. In contrast, the (S)-proline-derived precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one 6 gave (S)-N-formylprolylamides 9 and/or (S)-prolylamides 8 depending on the reaction conditions. Upon reduction with LiAlH4, amides 4 and 9 afforded the proline-derived (S)-2-(alkylaminomethyl)pyrrolidines 1 and (S)-N-methyl-2-(alkylaminomethyl)-pyrrolidines 5 in 70-90% yields.
