76411-80-8 Usage
General Description
(S)-1-METHYL-2-(1-PYRROLIDINYLMETHYL)PYRROLIDINE, also known as (S)-MPMP, is a chemical compound with a molecular formula of C13H22N2. It is a chiral compound, with its enantiomer (R)-MPMP also existing. (S)-MPMP is commonly used as a biochemical research tool to study the effects of GABA receptors in the central nervous system. It is known to exhibit both sedative and anxiolytic effects, making it a potential candidate for the development of new medications for the treatment of anxiety and related disorders. The compound is also commonly studied for its potential as a catalyst in organic synthesis and as a precursor in the development of new pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 76411-80-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,4,1 and 1 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 76411-80:
(7*7)+(6*6)+(5*4)+(4*1)+(3*1)+(2*8)+(1*0)=128
128 % 10 = 8
So 76411-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H20N2/c1-11-6-4-5-10(11)9-12-7-2-3-8-12/h10H,2-9H2,1H3/t10-/m1/s1
76411-80-8Relevant articles and documents
Synthesis of chiral diamines using novel 2-trichloromethyloxazolidin-4-one precursors derived from 5-oxo-proline and proline
Amedjkouh, Mohamed,Ahlberg, Per
, p. 2229 - 2234 (2007/10/03)
Efficient syntheses of chiral vicinal diamines derived from (S)-oxo-proline and (S)-proline are described. The novel diastereomerically pure precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo-[3.3.0]-octan-4,8-dione 3 and its enantiomer are readily available by reaction of the inexpensive enantiomers of 5-oxo-proline with chloral. Compound 3 reacts with primary and secondary amines to afford the 5-oxo-prolylamides 4 in quantitative yield. In contrast, the (S)-proline-derived precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one 6 gave (S)-N-formylprolylamides 9 and/or (S)-prolylamides 8 depending on the reaction conditions. Upon reduction with LiAlH4, amides 4 and 9 afforded the proline-derived (S)-2-(alkylaminomethyl)pyrrolidines 1 and (S)-N-methyl-2-(alkylaminomethyl)-pyrrolidines 5 in 70-90% yields.
