76432-88-7

Upstream product

• 60585-74-2 N-(1,2,5-trimethylpiperidylidene-4)aniline 
• 60585-74-2 1,2,5-trimethyl-4-N-phenyliminopiperidine 
• 122795-27-1 N-Phenyl-N-(1,2,5-trimethyl-4-piperidinyl)formamide 
• 7516-33-8 1,2,5-trimethyl-4-piperidone 
• 62-53-3 aniline 

Downstream Products

• 42045-99-8 1,2,5-Trimethyl-4-(propionylphenylamino)piperidine 
• 136038-90-9 1,2,5-trimethyl-4-aminopiperidine 
• 129115-38-4 N-Phenyl-N-(1,2,5-trimethyl-4-piperidinyl)benzylamine 
• 129115-39-5 N-Phenyl-N-(1,2,5-trimethyl-4-piperidinyl)p-methoxybenzylamine 
• 113556-61-9 N-Phenyl-N-(1,2,5-trimethyl-piperidin-4-yl)-benzamide 
• 95640-03-2 N-(1,2,5-trimethylpiperidyl-4)-propanilide 
• 78028-34-9 2-Chloro-N-phenyl-N-(1,2,5-trimethyl-piperidin-4-yl)-acetamide 
• 107973-25-1 N-(1,2,5-Trimethylpiperidin-4-yl)-N-(1,2-dimethoxycarbonyletheno)aniline 
• 76432-88-7 1,2e,5a-trimethyl-4e-phenylaminopiperidine 
• 76432-88-7 1,2e,5e-trimethyl-4e-phenylaminopiperidine 
• 78028-41-8 2-Dimethylamino-N-phenyl-N-(1,2,5-trimethyl-piperidin-4-yl)-acetamide 
• 78028-42-9 2-Diethylamino-N-phenyl-N-(1,2,5-trimethyl-piperidin-4-yl)-acetamide 
• 78028-43-0 N-Phenyl-2-pyrrolidin-1-yl-N-(1,2,5-trimethyl-piperidin-4-yl)-acetamide 
• 78028-44-1 N-Phenyl-2-piperidin-1-yl-N-(1,2,5-trimethyl-piperidin-4-yl)-acetamide 

Relevant academic research and scientific papers

BENZYLATION OF γ-N-(ARYLAMINO)PIPERIDINES VIA THE WALLACH REACTION

N-Aryl(aralkyl)-N-(4-piperidinyl)benzylamines have been prepared from γ-N-(arylamino)piperidines using the Wallach reaction.Carbonyl-containing compounds have been detected as impurities in these products using mass spectrometry.A possible mechanism is discussed for the Wallach reaction, based on the structures of the secondary amine starting materials used in this study.

1-METHYL(BENZYL)-2,5-DIMETHYL-4-N-PIPERIDINES AND THEIR ACYL DERIVATIVES

N-Substituted γ-aminopiperidines and their benz- and propioamides have been synthetized from γ-piperidones.The stereoisomeric amines and amides have been separated and identified.

1H AND 13C NMR SPECTRA AND THREE DIMENSIONAL STRUCTURES OF 1,2,5-TRIMETHYL-4-PHENYLAMINOPIPERIDINE ISOMERS

The three-dimensional structures of two isomers of 1,2,5-trimethyl-4-phenylaminopiperidine were established on the basis of analysis of their 1H and 13C NMR spectra.The piperidine ring has a chair conformation in both isomers.The δ isomer has the 1,2e,5a,