76436-33-4

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 16546-01-3 ethyl 3-(4-methoxyphenyl)-2,3-epoxypropionate 

Downstream Products

• 76451-12-2 Toluene-4-sulfonic acid (3R,4S)-5,7-dimethoxy-4-(4-methoxy-phenyl)-2-oxo-chroman-3-yl ester 
• 76436-37-8 trans-3-acetoxy-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-2-one 
• 123731-50-0 5,7-dimethoxy-3-(4-methoxyphenyl)-2H-1-benzopyran-2-one 
• 76436-36-7 trans-3-hydroxy-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-2-one 
• 76451-12-2 Toluene-4-sulfonic acid (3S,4S)-5,7-dimethoxy-4-(4-methoxy-phenyl)-2-oxo-chroman-3-yl ester 
• 76436-37-8 cis-3-acetoxy-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-2-one 
• 76436-36-7 cis-3-hydroxy-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-2-one 

Relevant academic research and scientific papers

Some Novel Photochemical and Related Aryl Couplings and Migrations in Flavonoid Synthesis

2'-Methoxymethoxy-4,4',6'-trimethoxychalcone epoxide couples at the β-position with 3,5-dimethoxyphenol under photolytic conditions to form isomeric 1,3,3-triaryl-2-hydroxypropiophenones.These propiophenones are subject to photo-induced α-ketol rearrangements yielding isomeric 1-hydroxypropan-2-ones.Together these serve as useful synthetic intermediates for 4-arylflavan-3-ones and novel 2-hydroxy-2-arylbenzylbenzofuran-3(2H)-ones and 4-aryl-3-hydroxy-3,4-cis-dihydrocoumarins.The same epoxide reacts ionically under ambient conditions with 2,4,6-trihydroxybenzoic acid to afford a 3-O-benzoylpropiophenone intermediate, which provides novel access to isoflavones in high overall yield.Analogous coupling of phloroglucinol to epoxycinnamates gives diastereoisomeric 3,3-diaryl-2-hydroxypropionates which serve as precursors for 3,4-trans- and 3,4-cis-4-aryl-3-hydroxydihydrocoumarins and thence for 3-aryl- and 3-hydroxycoumarins.