76436-35-6

Basic information

• Product Name: (2R,3R)-2-Hydroxy-3-(4-methoxy-phenyl)-3-(2,4,6-trihydroxy-phenoxy)-propionic acid ethyl ester
• CAS NO: 76436-35-6
• Molecular Weight: 364.352
• Mol File: 76436-35-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-2-Hydroxy-3-(4-methoxy-phenyl)-3-(2,4,6-trihydroxy-phenoxy)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-2-Hydroxy-3-(4-methoxy-phenyl)-3-(2,4,6-trihydroxy-phenoxy)-propionic acid ethyl ester(76436-35-6)
• EPA Substance Registry System: (2R,3R)-2-Hydroxy-3-(4-methoxy-phenyl)-3-(2,4,6-trihydroxy-phenoxy)-propionic acid ethyl ester(76436-35-6)

Safety Data

• Hazardous Substances Data: 76436-35-6(Hazardous Substances Data)

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 16546-01-3 ethyl 3-(4-methoxyphenyl)-2,3-epoxypropionate 

Downstream Products

• 76451-12-2 Toluene-4-sulfonic acid (3S,4S)-5,7-dimethoxy-4-(4-methoxy-phenyl)-2-oxo-chroman-3-yl ester 
• 76436-37-8 cis-3-acetoxy-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-2-one 
• 76436-36-7 cis-3-hydroxy-5,7-dimethoxy-4-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-2-one 

Relevant articles and documents

Some Novel Photochemical and Related Aryl Couplings and Migrations in Flavonoid Synthesis

2'-Methoxymethoxy-4,4',6'-trimethoxychalcone epoxide couples at the β-position with 3,5-dimethoxyphenol under photolytic conditions to form isomeric 1,3,3-triaryl-2-hydroxypropiophenones.These propiophenones are subject to photo-induced α-ketol rearrangements yielding isomeric 1-hydroxypropan-2-ones.Together these serve as useful synthetic intermediates for 4-arylflavan-3-ones and novel 2-hydroxy-2-arylbenzylbenzofuran-3(2H)-ones and 4-aryl-3-hydroxy-3,4-cis-dihydrocoumarins.The same epoxide reacts ionically under ambient conditions with 2,4,6-trihydroxybenzoic acid to afford a 3-O-benzoylpropiophenone intermediate, which provides novel access to isoflavones in high overall yield.Analogous coupling of phloroglucinol to epoxycinnamates gives diastereoisomeric 3,3-diaryl-2-hydroxypropionates which serve as precursors for 3,4-trans- and 3,4-cis-4-aryl-3-hydroxydihydrocoumarins and thence for 3-aryl- and 3-hydroxycoumarins.