76444-51-4 Usage
Uses
Used in Pharmaceutical Industry:
4-BROMO-N-METHYL PIPERIDINE is used as a synthetic intermediate for the development of various drugs and pharmaceuticals. Its unique structure and properties contribute to the creation of new chemical entities and compounds, enhancing the therapeutic potential of medications.
Used in Organic Synthesis:
4-BROMO-N-METHYL PIPERIDINE is used as a reagent in organic synthesis and chemical reactions. It is instrumental in introducing the piperidine moiety into various organic molecules, broadening the scope of chemical reactions and the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 76444-51-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,4,4 and 4 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 76444-51:
(7*7)+(6*6)+(5*4)+(4*4)+(3*4)+(2*5)+(1*1)=144
144 % 10 = 4
So 76444-51-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H12BrN/c1-8-4-2-6(7)3-5-8/h6H,2-5H2,1H3
76444-51-4Relevant academic research and scientific papers
RING INVERSION EQUILIBRIA IN 4-CHLORO-, 4-BROMO-, AND 4-METHOXY-1-ALKYLPIPERIDINES IN A NON-POLAR SOLVENT
Bailey, Judith M.,Booth, Harold,Al-Shirayda, Hatif A.R.Y.,Trimble, Mary L.
, p. 737 - 744 (2007/10/02)
The position of ring inversion equilibrium (axial Requuatorial R) in 4-R-N-alkylpiperidines (R = Cl, Br, or OMe), dissolved in CFCl3-CDCl3, has been determined by (13)C n.m.r. spectroscopy at low temperatures.In all three series, change of NH to NMe produces a marked increase in the proportion of conformation with axial R.When R is OMe, further alterations in the N-substituent from Me to Et, Pri, and CH2CF3 do not affect the equilibrium significantly, but the signifficant changes observed when R is halogen can be related to the inductive effect of the N-substituent. (13)C Chemical shifts, proportions of conformations, and conformational free energy differences are recorded for all systems studied.
