76457-73-3

Upstream product

• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 5351-69-9 4-Phenyl-3-thiosemicarbazide 
• 5373-72-8 5-mercapto-4-phenyl-{1,2,4}triazole 
• 5373-72-8 4-phenyl-Δ²-1,2,4-triazoline-5-thione 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 3588-96-3 3-(methylsulfonyl)-4-phenyl-4H-1,2,4-triazole 

Relevant academic research and scientific papers

Rapid, stable, chemoselective labeling of thiols with Julia- Kocienski-like reagents: A serum-stable alternative to maleimide-based protein conjugation

Exquisite chemoselectivity for cysteine has been found for methylsulfonylphenyloxadiazole compounds under various buffer conditions. Furthermore, the resulting protein conjugates have superior stability to cysteine-maleimide conjugates in human plasma (HS

The Synthesis of 4-Substituted-4H-1,2,4-triazole-3-thiols and 3-Methylthio-4-substituted-4H-1,2,4-triazoles

The synthesis of 4-substituted-4H-1,2,4-triazole-3-thiols and 3-methylthio-4-substituted-4H-1,2,4-triazoles by the condensation of 4-substituted-3-thiosemicarbazides with dimethylformamide dimethyl acetal or dimethylacetamide dimethyl acetal is described.A discussion of the mechanistic pathway is included.