5373-72-8Relevant articles and documents
Mononuclear Ni(II) and dinuclear Cd(II) complexes of 4-phenyl-2H-1,2,4- triazole-3-thione and Mn(II) catalyzed disulphide bond formation in 3,3′-dithiobis (4-phenyl-1,2,4-triazole): Syntheses, structural characterization, thermal analysis and DFT calculat
Dani,Bharty,Paswan,Singh, Sanjay,Singh
, p. 519 - 530 (2014)
New complexes [Ni(phtt)2(en)2] (2) and [Cd 2(μ-phtt)2(phtt)2(bpy)2] (3) have been synthesized by the reactions of M(NO3)2· xH2O and 4-phenyl-2H-1,2,4-triazo
Synthesis and antimicrobial and pharmacological properties of new thiosemicarbazide and 1,2,4-triazole derivatives
Popiolek, Lukasz,Dobosz, Maria,Chodkowska, Anna,Jagiello-Wojtowicz, Ewa,Kosikowska, Urszula,Malm, Anna,Mazur, Liliana,Rzaczynska, Zofia
body text, p. 339 - 346 (2011/06/19)
Reaction of 4-phenyl-4H-1,2,4-triazole-3-thione with ethyl bromoacetate has led to the formation of ethyl [(4-phenyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetate 1, the structure of which was confirmed by X-ray analysis. In the next reaction with 80% hydrazide hydrate, appropriate hydrazide 2 was obtained, which in reaction with isothiocyanates was converted to new acyl derivatives of thiosemicarbazides 3a-3h. The cyclization of these compounds in alkaline media has led to formation of new derivatives of 5-{[(4-phenyl-4H-1,2,4-triazole-3-yl) sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thiones 4a-4g, 4j. The structure of the compounds was confirmed by elementary analysis and IR, 1H-NMR, 13C-NMR, and MS spectra. Compounds 3a-3h and 4a-4g were screened for their antimicrobial activities, and the influence of the compounds 4a, 4b, and 4e-4g on the central nervous system of mice in behavioral tests was examined.
The reactions of cyclization of thiosemicarbazide derivatives to 1,2,4-triazole or 1,3,4-thiadiazole system
Dobosz, Maria,Pitucha, Monika,Wujec, Monika
, p. 31 - 38 (2007/10/03)
In the reaction of hydrazide of formic, nicotinic and benzoic acid with isothiocyanates were obtained the respective thiosemicarbazide derivatives [I-XII]. Further cyclization with 2% NaOH solution led to formation of derivatives Δ2-1,2,4-triaz