76462-17-4

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-3-Methylbenzenethiol is used as a starting material for the synthesis of various pharmaceutical drugs, including antihypertensive agents and other medicinally active compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic benefits.
Used in Dye and Pigment Industry:
2-Amino-3-Methylbenzenethiol is used as a building block for the production of dyes, pigments, and other industrial chemicals. Its versatile chemical properties make it a valuable component in the creation of a wide range of colorants and specialty chemicals for various applications.

Upstream product

• 614-78-8 o-tolylthiourea 
• 3048-48-4 4-methylbenzo[d]thiazole 
• 53065-21-7 2-amino-4-methylbenzothiazole hydrobromide 
• 636-21-5 o-toluidine hydrochloride 

Downstream Products

• 121364-15-6 Biphenyl-4-yl-(3,5-dimethyl-4H-benzo[1,4]thiazin-2-yl)-methanone 
• 126308-12-1 (2,4-Dimethoxy-phenyl)-(3,5-dimethyl-4H-benzo[1,4]thiazin-2-yl)-methanone 
• 93075-16-2 2-methyl-6-(2-nitro-phenylsulfanyl)-aniline 
• 93091-65-7 2-Methyl-6-(2-nitro-4-trifluoromethyl-phenylsulfanyl)-phenylamine 
• 79838-65-6 4-(2-Amino-3-methyl-phenylsulfanyl)-3-nitro-benzoic acid 
• 500898-54-4 2-(2-chloro-6-nitro-phenylsulfanyl)-6-methyl-phenylamine 
• 500898-56-6 2-(4,5-dichloro-2-nitro-phenylsulfanyl)-6-methyl-phenylamine 
• 690243-03-9 2-(2-chloro-5-nitro-phenyl)-4-methyl-benzothiazole 
• 79838-68-9 4-(2-Formylamino-3-methyl-phenylsulfanyl)-3-nitro-benzoic acid 
• 79838-69-0 N-[2-(2,4-Dinitro-phenylsulfanyl)-6-methyl-phenyl]-formamide 
• 111281-05-1 N-[2-(3,5-Dibromo-2-nitro-phenylsulfanyl)-6-methyl-phenyl]-formamide 
• 146070-31-7 3-Trifluoromethyl-2-(3-methyl-2-aminophenylthio)-benzonitrile 
• 1169760-20-6 (S)-2-methyl 3-(2-amino-3-methylbenzenethio)-propanol 
• 220328-24-5 benzyl 3,5-dimethyl-4H-1,4-benzothiazine-2-carboxylate 

Relevant academic research and scientific papers

Novel SIRT 1 activator and medical use thereof

The present invention relates to a SIRT 1 activator and medical uses thereof. In the present invention, a novel SIRT 1 activator compound based on a benzo[d]thiazole skeleton, a crystalline form thereof, a hydrate thereof or a salt thereof is prepared, and effect on alleviating obesity, insulin resistance and dyslipidemia, alleviating fatty liver, preventing cell aging, preventing oxidative stress and extending of life of yeast. Therefore, the novel SIRT 1 activator compound having the above effects can be used for a pharmaceutical composition for therapeutic use for preventing or treating metabolic diseases including obesity, diabetes mellitus, dyslipidemia and the like and liver diseases including alcoholic or non-alcoholic fatty liver, fatty liver diseases and the like, and a health food composition for alleviating cell aging or prolonging the life span, and the like.COPYRIGHT KIPO 2018

Synthesis of bioactive substituted pyrazolylbenzothiazinones

Abstract Pyrazolylbenzothiazinones have been synthesized in good yields by the reaction of 2-hydrazinocarbonymethyl-3,4-dihydro-2H-1,4-benzothiazin-3-ones with β-diketone in the presence of ethanol. The structures of synthesized pyrazolylbenzothiazinones were confirmed on the basis of their analytical and spectral data. The antimicrobial activities of the synthesized compounds have also been included.

Synthesis and antioxidant activity of quinolinobenzothiazinones

A new series of structurally diverse quinolinobenzothiazinones has been synthesized with the annulation of heterocyclic structural pharmacophores. The synthesized quinolinobenzothiazinones have been evaluated for their antioxidant (LPO & GSH) and radical scavenging activities (DPPH and ABTS assays).