764650-97-7Relevant academic research and scientific papers
Enantioselective thiourea-catalyzed acyl-Mannich reactions of isoquinolines
Taylor, Mark S.,Tokunaga, Norihito,Jacobsen, Eric N.
, p. 6700 - 6704 (2007/10/03)
(Chemical Equation Presented) Inexpensive aromatic feedstocks are substrates for highly enantioselective acylative Mannich reactions catalyzed by a thiourea chiral hydrogen-bond donor 1. This methodology provides access to useful 1-substituted dihydroisoq
Highly enantioselective catalytic acyl-Pictet-Spengler reactions
Taylor, Mark S.,Jacobsen, Eric N.
, p. 10558 - 10559 (2007/10/03)
The enantioselective cyclization of N-acyliminium ions generated in situ from tryptamine is promoted with high enantioselectivity by a new chiral thiourea catalyst. This represents the first successful system for asymmetric catalysis of the Pictet-Spengle
