764658-24-4Relevant academic research and scientific papers
Discovery of new chemical leads for prostaglandin D2 receptor antagonists
Torisu, Kazuhiko,Kobayashi, Kaoru,Iwahashi, Maki,Egashira, Hiromu,Nakai, Yoshihiko,Okada, Yutaka,Nanbu, Fumio,Ohuchida, Shuichi,Nakai, Hisao,Toda, Masaaki
, p. 4557 - 4562 (2004)
A series of Indomethacin analogs were synthesized and biologically evaluated. Among the compounds tested, N-(p-butoxy)benzoyl-2-methylindole-4- acetic acid 2 was discovered as a new chemical lead for a prostaglandin D 2 (PGD2) recept
Development of a prostaglandin D2 receptor antagonist: Discovery of a new chemical lead
Torisu, Kazuhiko,Kobayashi, Kaoru,Iwahashi, Maki,Egashira, Hiromu,Nakai, Yoshihiko,Okada, Yutaka,Nanbu, Fumio,Ohuchida, Shuichi,Nakai, Hisao,Toda, Masaaki
, p. 505 - 519 (2007/10/03)
A series of N-(p-alkoxy)benzoyl-5-methoxy-2-methylindole-3-acetic acids and N-(p-butoxy)benzoyl-2-methylindole-4-acetic acid were discovered as new chemical leads for a prostaglandin D2 (PGD2) receptor antagonist. Most of them exhibi
