764659-49-6

Basic information

• Product Name: (1S,2R)-{2-[(3-chloro-1H-indole-6-carbonyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester
• Synonyms: (1S,2R)-{2-[(3-chloro-1H-indole-6-carbonyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester
• CAS NO: 764659-49-6
• Molecular Weight: 391.898
• Mol File: 764659-49-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,2R)-{2-[(3-chloro-1H-indole-6-carbonyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-{2-[(3-chloro-1H-indole-6-carbonyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester(764659-49-6)
• EPA Substance Registry System: (1S,2R)-{2-[(3-chloro-1H-indole-6-carbonyl)-amino]-cyclohexyl}-carbamic acid tert-butyl ester(764659-49-6)

Safety Data

• Hazardous Substances Data: 764659-49-6(Hazardous Substances Data)

Upstream product

• 365996-28-7 (1S,2S)-2-(tert-butoxycarbonylamino)cyclohexyl methanesulfonate 
• 365996-29-8 (1R,2S)-2-(N-tert-butyloxycarbonylamino)-1-azidocyclohexane 
• 216394-07-9 1-(S)-trans-(S)-2-phenylmethoxycyclohexylamine 
• 121282-70-0 (1S,2S)-2-tert-Butoxycarbonylamino-1-cyclohexanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 764659-69-0 tert-butyl [(1S,2S)-2-(benzyloxy)cyclohexyl]carbamate 
• 219508-17-5 3-chloro-1H-indole-6-carboxylic acid 
• 365996-30-1 tert-butyl ((1S,2R)-2-aminocyclohexyl)carbamate 

Downstream Products

• 764659-50-9 (1R, 2S)-3-chloro-1H-indole-6-carboxylic acid (2-amino-cyclohexyl)-amide 

Relevant articles and documents

SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa

In the search of Factor Xa (FXa) inhibitors structurally different from the pyrazole-based series, we identified a viable series of enantiopure cis-(1R,2S)-cycloalkyldiamine derivatives as potent and selective inhibitors of FXa. Among them, cyclohexyldiam