764708-27-2

Usage

Uses

Used in Pharmaceutical Industry:
4-Pyridineethanamine,2-methoxy-(9CI) serves as an essential intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medical treatments.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Pyridineethanamine,2-methoxy-(9CI) is utilized as an intermediate for the production of pesticides and other agrochemicals. Its role in this industry is crucial for the development of effective solutions to protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
4-Pyridineethanamine,2-methoxy-(9CI) acts as a building block in the creation of a wide range of organic compounds. Its presence in organic synthesis is significant, as it enables the production of various chemical entities that can be applied in different fields, further expanding its utility and impact.

InChI:InChI=1/C8H12N2O/c1-11-8-6-7(2-4-9)3-5-10-8/h3,5-6H,2,4,9H2,1H3

Upstream product

• 102336-07-2 3-(2-methoxypyridin-4-yl)propanoic acid 
• 123148-66-3 2-methoxy-4-(hydroxymethyl)-pyridine 
• 58481-11-1 methyl 2-chloroisonicotinate 
• 26156-51-4 methyl 2-methoxyisonicotinate 
• 355013-79-5 4-(chloromethyl)-2-methoxypyridine 

Downstream Products

• 1395552-82-5 2-(4-bromo-3-fluorophenyl)-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-methylpyrimidin-4-amine 
• 764708-39-6 C₁₈H₁₆BrFN₄O 
• 795266-61-4 4-(2-{[2-(4-chloro-2,5-difluorophenyl)-6-ethylpyrimidin-4-yl]amino}ethyl)pyridin-2(1H)-one 
• 1395552-94-9 2-(4-chloro-2,5-difluorophenyl)-6-ethyl-N-[2-(2-methoxypyridin-4-yl)ethyl]pyrimidin-4-amine 
• 794485-71-5 4-(2-{[2-(4-chloro-2,5-difluorophenyl)-6-methylpyrimidin-4-yl]amino}ethyl)pyridin-2(1H)-one 
• 1395552-89-2 2-(4-chloro-2,5-difluorophenyl)-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-methylpyrimidin-4-amine 
• 764708-29-4 4-(2-{[2-(4-Bromo-2,5-difluorophenyl)-6-methylpyrimidin-4-yl]amino}ethyl)pyridin-2(1H)-one 
• 764708-28-3 2-(4-bromo-2,5-difluorophenyl)-N-[2-(2-methoxypyridin-4-yl)ethyl]-6-methylpyrimidin-4-amine 
• 170026-06-9 N-n-propyl-N-<2-(2-methoxy-4-pyridyl)ethyl>-2-phenylethanamide 
• 170026-09-2 N-propyl-N-(2-phenylethyl)-2-(2-methoxy-4-pyridyl)ethylamine 

Relevant academic research and scientific papers

Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists

Novel 4-amino-2-phenylpyrimidine derivatives were synthesized and evaluated as GPR119 agonists. Optimization of the substituents on the phenyl ring at the 2-position and the amino group at the 4-position led to the identification of 3,4-dihalogenated and

New 2-pyridylethylamines with dopaminergic activity: Synthesis and radioligand-binding evaluation

In order to determine whether the pyridine nucleus could replace the catechol moiety of the neurotransmitter dopamine or the phenol ring of the dopaminergic pharmacophore m-hydroxyphenylethylamine, the 2-(3-pyridyl)ethylamine 7, 2-(4-pyridyl)ethylamine 8, 2-(2-hydroxy-4-pyridyl)ethylamine 10 and their N,N-di-n-propyl- and N-n-propyl-N-2-phenylethyl derivatives were synthesized. The affinities of the new compounds for D1 and D2 dopamine receptors were evaluated by displacement of [3H]SCH 23390 (D1 selective) and [3H]spiperone (D2 selective) on rat neostriatum sections. The 2-(4-pyridyl)ethylamine 8 and its N,N-di-n-propyl derivative 18 showed the same affinity for the D1 and D2 receptors. Other compounds bound to the D1 receptor with higher affinity than to the D2 receptor. The possibility that the above compounds act as agonists and antagonists at the dopamine D1 and D2 receptors is discussed on the basis of guanosine-5'-triphosphate and Na+ displacement curves.