764717-72-8

Basic information

• Product Name: N-4-methoxyphenyl-N-phenylamino acetonitrile
• Synonyms: N-4-methoxyphenyl-N-phenylamino acetonitrile
• CAS NO: 764717-72-8
• Molecular Weight: 238.289
• Mol File: 764717-72-8.mol

Chemical Properties

• CAS DataBase Reference: N-4-methoxyphenyl-N-phenylamino acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: N-4-methoxyphenyl-N-phenylamino acetonitrile(764717-72-8)
• EPA Substance Registry System: N-4-methoxyphenyl-N-phenylamino acetonitrile(764717-72-8)

Safety Data

• Hazardous Substances Data: 764717-72-8(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 74-90-8 hydrogen cyanide 
• 1208-86-2 N-(4-methoxyphenyl)phenylamine 
• 590-17-0 cyanomethyl bromide 
• 107-14-2 chloroacetonitrile 

Relevant articles and documents

N-(substituted-anilinoethyl)amides: Design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands

A novel series of melatonin receptor ligands, characterized by a N-(substituted-anilinoethyl)amido scaffold, along with preliminary structure-activity relationships (SARs), is presented. MT1 and MT2 receptor binding affinity and intr

NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES

Novel melatonin ligands of Formula (I) or pharmaceutically acceptable salts thereof wherein: n is 1 or 2; m is 0, 1 or 2; p is 0, 1, 2, 3, 4, 5, 6, 7 or 8; v is 2 or 3; A is aryl or heteroaryl; Z is O, S or NR8;Y is selected from the group consisting of hydrogen, aryl, heteroaryl, CrC6 alkyl, C3-C6 cycloalkyl, and R is selected from the group consisting of hydrogen, hydroxyl, -OCF3, CF3, C1-C8 alkyl, C1C8 alkyloxy, C1C8 alkylthio, halogen and -Z-(CH2)P-A; R1 is selected from the group consisting of C1C4 alkyl, C3-C6 cycloalkyl, CF3, hydroxy-substituted C1C4 alkyl, hydroxy-substituted C3-C6 cycloalkyl, and NHR5, wherein R5 is C1C3 alkyl or C3-C6 cycloalkyl; R2 is selected from the group consisting of: hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; R3 is selected from the group consisting of hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; R and R3 may be connected together to form an -0-(CH2)v bridge representing with the carbon atoms to which they are attached a 5- or 6-membered heterocyclic ring system; R4 is selected from the group consisting of hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; R6 is selected from the group consisting of hydrogen and C1C6 alkyl; R7 is selected from the group consisting of hydrogen, C1C4 alkyl, C1C4 alkyloxy, OCF3, CF3, hydroxyl, and halogen; and R8 is selected from the group consisting of hydrogen and C1C4 alkyl.

Alkylation of diphenylamines with chloroacetonitrile: A new entry to phentolamine analogues

The alkylation of diphenylamines with chloroacetonitrile followed by annulation with ethylenediamine gave 2-imidazoline analogues of phentolamine.