764718-05-0

Basic information

• Product Name: 2-Pyrrolidinone,1-cyclopentyl-5-methyl-(9CI)
• Synonyms: 2-Pyrrolidinone,1-cyclopentyl-5-methyl-(9CI)
• CAS NO: 764718-05-0
• Molecular Formula: C10H17NO
• Molecular Weight: 167.24808
• Product Categories: AMINETERTIARY
• Mol File: 764718-05-0.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyrrolidinone,1-cyclopentyl-5-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone,1-cyclopentyl-5-methyl-(9CI)(764718-05-0)
• EPA Substance Registry System: 2-Pyrrolidinone,1-cyclopentyl-5-methyl-(9CI)(764718-05-0)

Safety Data

• Hazardous Substances Data: 764718-05-0(Hazardous Substances Data)

Upstream product

• 539-88-8 4-oxopentanoic acid ethyl ester 
• 1003-03-8 Cyclopentamine 
• 123-76-2 levulinic acid 

Relevant articles and documents

Reductive amination of levulinic acid to N-substituted pyrrolidones over RuCl3 metal ion anchored in ionic liquid immobilized on graphene oxide

Reductive amination of biomass derived Levulinic acid (LA) for the synthesis of N-substituted pyrrolidones is one of the highly attractive routes for biomass valorization. The supported homogeneous metal precursor into the solid surface is an important context in the field of catalysis because these types of catalysts provide the heterogeneous nature and meet the needs of recyclability. Herein, we have reported a synthesis of catalyst with ruthenium ion supported on ionic liquid immobilized into graphene oxide (Ru?GOIL) and its application for reductive amination reaction. Synthesized catalyst is characterized using different analytical techniques such as FT-IR, XRD, XPS, TGA, FEG-SEM, TEM and EXAFS analysis. The prepared Ru?GOIL found to be highly effective for reductive amination of LA and under these optimized conditions various N-substituted pyrrolidones derivatives were synthesized in excellent yield (78–93%). Ru?GOIL catalyst demonstrated great catalytic performance for reductive amination reaction of LA giving good turnover frequency (TOF = 62 h?1) value in comparison with other catalysts. The Ru?GOIL catalyst was recycled for six reaction runs with slight drop-in activity after 4th cycle. Practical applicability of the developed catalyst was successfully demonstrated by direct transformation of biomass waste (rice husk and wheat straw) derived LA to N-substituted pyrrolidones.

Lactate-Based Ionic Liquid Catalyzed Reductive Amination/Cyclization of Keto Acids under Mild Conditions: A Metal-Free Route to Synthesize Lactams

Task-specific ionic liquids (ILs) have shown promising applications in catalysis. Herein we present lactate-based IL (e.g., 1-butyl-3-methylimidazolium lactate, [BMIm][Lac]) catalyzed reductive amination/cyclization of keto acids using triethoxysilane as a reducing agent, which provides a metal-free route to synthesis of lactams under mild conditions, even at room temperature. [BMIm][Lac] combined with (EtO)3SiH afforded a series of five- and six-membered lactams in good to excellent yields at 80 °C within 1 h, showing comparable performance to the best metal-based catalyst reported to date. The mechanism investigation indicated that the ILs (e.g., [BMIm][Lac]) served as a multifunctional catalyst, which could activate hydrosilanes and simultaneously catalyzed the cyclization of LA with amines.

Production of 5-mehyl-N-aryl-2-pyrrolidone and 5-methyl-N-alkyl-2-pyrrolidone by reductive of levulinic acid esters with aryl and alkyl amines

This invention relates to a process for producing 5-methyl-N-aryl-2-pyrrolidone, 5-methyl-N-alkyl-2-pyrrolidone, and 5-methyl-N-cycloalkyl-2-pyrrolidone by reductive amination of levulinic acid esters with aryl or alkyl amines utilizing a metal catalyst, which is optionally supported.