76480-70-1Relevant academic research and scientific papers
Chemistry of 2-Substituted Pyrimidines. Studies Directed toward the Synthesis of the Pyrimidine Moiety of Bleomycin
Hagmann, William K.,Basha, Fatima Z.,Hashimoto, Mitsunori,Frye, Bruce R.,Kojo, Shosuke,Hecht, Sidney M.
, p. 1413 - 1423 (2007/10/02)
Synthetic approaches to 2-substituted pyrimidines have been studied in an effort to facilitate the preparation of the pyrimidine moiety of bleomycin (2).Ethyl 2,5-dimethyl-4-oxopyrimidine-6-carboxylate (4) has been utilized as starting material; its conve
