39875-10-0

Usage

Uses

Used in Pharmaceutical Industry:
2,5-dimethyl-6-oxo-3,6-dihydropyrimidine-4-carboxylic acid is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its versatile molecular structure allows it to be a key component in the development of antiviral, anticancer, and antibacterial drugs, contributing to the advancement of medical treatments and therapies.

Upstream product

• 76480-84-7 Potassium 2,5-Dimethyl-4-pyrimidine-6-carboxylate 
• 759-65-9 diethyl oxalpropionate 

Downstream Products

• 39875-11-1 2-(2-Hydroxy-3,3,3-trichloropropyl)-5-methyl-4-oxopyrimidine-6-carboxylic Acid 
• 76480-61-0 Ethyl 4-Amino-2,5-dimethylpyrimidine-6-carboxylate 
• 76498-32-3 Ethyl 4-Chloro-2,5-dimethylpyrimidine-6-carboxylate 
• 76480-50-7 Ethyl 5-Methyl-2-(tribromomethyl)-4-oxopyrimidine-6-carboxylate 
• 76480-70-1 5-Methyl-2-(3,3,3-trichloro-trans-1-propenyl)-4-oxopyrimidine-6-carboxylic Acid 
• 76480-72-3 Ethyl trans-3-<6-(Carboethoxy)-5-methyl-4-oxopyrimidin-2-yl>acrylate 
• 76480-85-8 p-Tolyl 6-(Carboethoxy)-5-methyl-4-oxopyrimidine-2-thiocarboxylate 
• 76480-66-5 Ethyl 2-(N-Benzylcarboxamido)-5-methyl-4-oxopyrimidine-6-carboxylate 
• 76480-77-8 Ethyl 3-<4-Azido-6-(carboethoxy)-5-methylpyrimidin-2-yl>-3-(benzylamino)propionate 
• 76498-35-6 Ethyl 3-<4-Azido-6-(carboethoxy)-5-methylpyrimidin-2-yl>-3-<<2-<<(benzyloxy)carbonyl>amino>-2-carboxamidoethyl>amino>propionate 
• 74536-25-7 Ethyl 2,5-Dimethyl-4-oxopyrimidine-6-carboxylate 

Relevant academic research and scientific papers

NEW CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.

NEW SELECTIVE CCR2 ANTAGONISTS

The present invention relates to novel and selective antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD as well as pain.

Chemistry of 2-Substituted Pyrimidines. Studies Directed toward the Synthesis of the Pyrimidine Moiety of Bleomycin

Synthetic approaches to 2-substituted pyrimidines have been studied in an effort to facilitate the preparation of the pyrimidine moiety of bleomycin (2).Ethyl 2,5-dimethyl-4-oxopyrimidine-6-carboxylate (4) has been utilized as starting material; its conve