765-71-9

Usage

Compound class

Pyrrole (a five-membered ring with one nitrogen atom)

State

Colorless liquid

Odor

Strong and unpleasant

Primary use

Synthesis of pharmaceuticals and other organic compounds

Also used as

Building block in the production of other chemicals

Value in field

Valuable compound in organic chemistry

InChI:InChI=1/C6H10N2/c1-5-3-4-6(2)8(5)7/h3-4H,7H2,1-2H3

Upstream product

• 101938-64-1 benzyl (2,5-dimethyl-1H-pyrrol-1-yl)carbamate 
• 628-16-0 hexa-1,5-diyne 
• 143800-06-0 1-Formamino-2,5-dimethyl-pyrrol 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 32558-63-7 N-(2,5-dimethyl-1H-pyrrol-1-yl)benzamide 

Relevant academic research and scientific papers

Oxalohydrazide Ligands for Copper-Catalyzed C?O Coupling Reactions with High Turnover Numbers

Here, we report a class of ligands based on oxalohydrazide cores and N-amino pyrrole and N-amino indole units that generates long-lived copper catalysts for couplings that form the C?O bonds in biaryl ethers. These Cu-catalyzed coupling of phenols with aryl bromides occurred with turnovers up to 8000, a value which is nearly two orders of magnitude higher than those of prior couplings to form biaryl ethers and nearly an order of magnitude higher than those of any prior copper-catalyzed coupling of aryl bromides and chlorides. This ligand also led to copper systems that catalyze the coupling of aryl chlorides with phenols and the coupling of aryl bromides and iodides with primary benzylic and aliphatic alcohols. A wide variety of functional groups including nitriles, halides, ethers, ketones, amines, esters, amides, vinylarenes, alcohols and boronic acid esters were tolerated, and reactions occurred with aryl bromides in pharmaceutically related structures.

Gold-catalyzed hydroamination of alkynes and allenes with parent hydrazine

A diverse array of nitrogen-containing compounds were formed by the addition of hydrazine to alkynes, diynes, enynes, and allenes in the presence of cationic gold(I) complexes with a cyclic (alkyl)(amino)carbene ligand (see scheme; the X-ray crystal structure of the gold-hydrazine complex is shown). This hydroamination is an ideal initial step for the preparation of acyclic and heterocyclic bulk chemicals. Dipp=2,6-diisopropylphenyl. Copyright

1-aminoacetamidopyrroles and 1-aminoacetamido-2-(substituted)pyrroles and related compounds

There are disclosed 1-aminoacetamidopyrroles and 1-amino-2-(substituted)-pyrroles and related compounds of the formula STR1 wherein all substituents are defined herein, which are useful as glycine partial agonists and for the enhancement of learning and memory and for the treatment of memory dysfunctions associated with neurodegenerative disorders and are thus indicated in the treatment of Alzheimer''s disease and other senile dementias.

Herbicidal and plant-growth-regulating N-substituted-N-(2,5-dialkylpyrrol-1-yl) haloacetamides

Compounds of the formula: STR1 wherein R1 and R2 are alkyl or halo; R3 is hydrogen or alkyl; Z is halo; and R4 is alkoxycarbonyl, alkoxy, phenyl, substituted phenyl, a group of the formula STR2 wherein R5 and R6 are hydrogen, alkyl, alkenyl or alkynyl; a group of the formula STR3 wherein R7 and R8 are hydrogen and alkyl; a five or six-membered aromatic heterocyclic ring of the formula STR4 wherein at least one of V, W, X or Y is an oxygen, sulfur or nitrogen atom, R9 is alkyl and n is 0, 1, 2 or 3 have herbicidal and plant-growth-regulating activity.