76502-94-8

Basic information

• Product Name: 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-isoglutamine methyl ester
• Synonyms: 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-isoglutamine methyl ester
• CAS NO: 76502-94-8
• Molecular Weight: 684.744
• Mol File: 76502-94-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-isoglutamine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-isoglutamine methyl ester(76502-94-8)
• EPA Substance Registry System: 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-isoglutamine methyl ester(76502-94-8)

Safety Data

• Hazardous Substances Data: 76502-94-8(Hazardous Substances Data)

Upstream product

• 2862-03-5 Benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-<(R)-1-carboxyethyl>-α-D-glucopyranoside 
• 76491-70-8 L-alanyl-D-isoglutamine-γ-methyl ester 
• 76491-69-5 benzyloxycarbonylalanyl-D-isoglutamine methyl ester 
• 13343-63-0 benzyl 4,6-O-benzylidene-2-acetylamino-2-deoxy-α-D-glucopyranoside 

Downstream Products

• 63092-13-7 1-O-benzyl-4,6-O-benzylidene-N-acetylmuramyl-alanyl-D-glutamic acid diamide 

Relevant articles and documents

SYNTHESIS OF PEPTIDES, GLYCO DERIVATIVES AND GLYCOPEPTIDES FROM BACTERIAL CELL WALLS

Synthesis in solution and in solid phase was used to prepare alanyl-D-isoglutamine (VI), alanyl-D-isoglutaminyl-Nε-p-toluenesulfonyl-lysyl-D-alanine methyl ester (XIII), alanyl-D-isoglutaminyl-Nε-acetyl-lysyl-D-alanine methyl ester (XIV), alanyl-D-isoglutaminyl-Nε-acetyl-lysyl-D-alanyl-pentaglycine methyl ester and amide (XXXI, XXXII), methyl ester (XXXV), methyl ester (XXXVII), N-acetylmuramyl-alanyl-D-isoglutaminyl-Nε-acetyl-lysyl-D-alanyl-pentaglycine amide (XXXIX), methyl ester (XLI), and methyl ester (XLIII).Thetetrapeptides, nonapeptides, and tridecapeptides show a pronounced pyrogenic effect.Imunoadjuvant activity was observed not only with the glycopeptides but also with nonapeptide XXXI.