76524-50-0Relevant academic research and scientific papers
B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of: In situ -formed enamines
Wu, Rongpei,Gao, Ke
, p. 4032 - 4036 (2021)
A highly efficient B(C6F5)3-catalyzed tandem protonation/deuteration and reduction of in situ-formed enamines in the presence of water and pinacolborane was developed. Regioselective β-deuteration of tertiary amines was achieved with high chemo- and regioselectivity. D2O was used as a readily available and cheap source of deuterium. Mechanistic studies indicated that B(C6F5)3 could activate water to promote the protonation and reduction of enamines. This journal is
SYNTHESIS OF α,β-UNSATURATED ALDEHYDES VIA 1-AMINOPROPA-1,2-DIENES: MECHANISTIC STUDIES
Craig, J. Cymerman,Ekwuribe, Nnochiri N.
, p. 2587 - 2590 (2007/10/02)
A facile prototropic rearrangement of N-(prop-2-ynyl)amines to 1-aminopropa-1,2-dienes, followed by acid hydrolysis, affords a novel synthesis of α,β-unsaturated aldehydes.The mechanism of the reaction has been examined by deuterium labeling.
