76525-19-4Relevant academic research and scientific papers
Diastereoselektive Hydroxyalkylierungen in 1-Stellung von Tetrahydroisochinolinen und Synthese von Aporphin-, Protoberberin- und Phthalid-Alkaloiden
Seebach,Dieter,Huber, Isabelle M. P.,Syfrig, Max A.
, p. 1357 - 1379 (2007/10/02)
Unsubstituted and 6,7-dialkyloxy-N-pivaloyl-tetrahydroisoquinolines 1-3 are converted to 1-bromomagnesium derivatives by sequential treatment with t-BuLi (-75 deg C/THF) and MgBr2*OEt2.Addition of the metalated tetrahydroisoquinolines to aliphatic or arom
Photocyclisation of 1-(2'-Halo-α-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolines; Synthesis of (+/-)-Oliveridine
Kessar, S. V.,Gupta, Y. P.,Mohammad, Taj
, p. 984 (2007/10/02)
In contrast to α-deoxy analogs, photocyclisation of 1-(2'-halo-α-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinolines to aporphines succeeds even in cyclohexane solvent, probably because of internal hydrogen bonding.A synthesis of the alkaloid oliveridine is de
SYNTHETIC PHOTOCHEMISTRY. SYNTHESIS OF (+/-)OLIVEROLINE AND (+/-)USHINSUNINE
Kessar, S.V.,Gupta, Y.P.,Yadav, V.S.,Narula, Mridu,Mohammad, Taj
, p. 3307 - 3308 (2007/10/02)
Sodium borohydride reduction of 1-(2'-Bromobenzoyl)-2-methyl-3,4-dihydro-6,7-methylenedioxyisoquinolinium iodide (4) gave a mixture of alcohols which on irradiation in dil.HCl afforded (+/-) oliveroline and (+/-) ushinsunine.
