76525-26-3

Upstream product

• 33798-66-2 oricine 
• 76525-28-5 N-methylpreskimmianine 
• 76525-27-4 7,8-dimethoxy-3,4,5,6-tetrahydro-2,2,6-trimethyl-5-oxo-2H-pyrano<3,2-c>quinoline 
• 38695-41-9 preskimmianine 
• 96838-24-3 6,7-Dimethoxy-3-[2-methyl-prop-(Z)-ylidene]-3,5-dihydro-furo[3,2-c]quinoline-2,4-dione 
• 96838-28-7 4-Hydroxy-7,8-dimethoxy-3-[2-methyl-prop-(E)-ylidene]-3H-furo[2,3-b]quinolin-2-one 
• 96838-77-6 (Z)-2-(4-Hydroxy-7,8-dimethoxy-2-oxo-1,2-dihydro-quinolin-3-yl)-4-methyl-pent-2-enoic acid 
• 96838-82-3 (4-Hydroxy-7,8-dimethoxy-2-oxo-1,2-dihydro-quinolin-3-yl)-acetic acid 
• 96838-72-1 4-Hydroxy-7,8-dimethoxy-3-((E)-3-methyl-but-1-enyl)-1H-quinolin-2-one 
• 38750-40-2 4-hydroxy-7,8-dimethoxy-3-(3-methyl-but-2-enyl)-1H-quinolin-2-one 
• 182205-45-4 benzyl 2,3-dimethoxyphenyl(methyl)carbamate 
• 182205-44-3 benzyl 2,3-dimethoxyphenylcarbamate 
• 83818-47-7 2,3-dimethoxy-N-methylaniline 
• 1521-38-6 2,3-dimethoxybenzoic acid 

Relevant academic research and scientific papers

VEPRISINE AND N-METHYLPRESKIMMIANINE : NOVEL 2-QUINOLONES FROM VEPRIS LOUISII

The structures of two new 2-quinolone alkaloids, N-methylpreskimmianine and veprisine (7,8-dimethoxy-N-methylflindersine) have been deduced from their spectra and confirmed by partial synthesis from known compounds.

Synthesis of Pyranoquinolin-5-one Alkaloids: Veprisine, 7-Dimethylallyloxy-N-methylflindersine and cis-3,4-Dihydroxy-7-methoxy-2,2,6-trimethyl-3,4,5,6-tetrahydro-2H-pyranoquinolin-5-one

Condensation of the appropriate 4-hydroxyquinolin-2-ones with 3-methylbut-2-enal gave pyranoquinolin-5-ones which were further elaborated to three alkaloids named in the title.

SRS-A Antagonist pyranoquinolone alkaloids from East African Fagara plants and their synthesis

Three pyranoquinolone alkaloids isolated from two East African Fagara plants have been found to exhibit SRS-A antagonist action. Their synthesis has been accomplished, using a modified Coppola's method or a thermal cyclization followed by an electrocyclic

A CONVENIENT SYNTHESIS OF FLINDERSINE, ATANINE AND THEIR ANALOGUES

A new synthesis of the pyranoquinolone alkaloids flindersine (8a), 8-methoxyflindersine (8c), N-methylflindersine (9a), zanthobunglanine (9c), oricine (9d) and veprisine (9e) and the prenylquinolone alkaloids atanine (13a), preskimmianine (13e), N-methylatanine (14a), O-methylglycosolone (14c) and N-methylpreskimmianine (14e) is described.

QUINOLINE AND INDOLOPYRIDOQUINAZOLINE ALKALOIDS FROM VEPRIS LOUISII

The structures of two new 2-quinolone alkaloids from the stem bark of Vepris louisii, N-methylpreskimmianine and veprisine (7,8-dimethoxy-N-methylflindersine) have been deduced from their spectral data and confirmed by partial synthesis from known compounds.Two minor indolopyridoquinazoline alkaloids were also isolated and identified as the already known 1-hydroxyrutaecarpine and the hitherto unknown 7,8-dehydro derivative of 1-hydroxyrutaecarpine. - Key Word Index: Vepris louisii; Rutaceae; stem bark; alkaloids; 2-quinolones; veprisine; N-methylpreskimmianine; indolopyridoquinazoline; 1-hydroxyrutaecarpine; 7,8-dehydro-1-hydroxyrutaecarpine.