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76530-89-7 Usage

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Used in Neurodegenerative Disease Treatment:
Bis(3,4-methylenedioxy)chalcone is used as a therapeutic agent for the treatment of amyloid diseases and synucleinopathies, including Alzheimer's disease, type 2 diabetes, and Parkinson's disease. Its potential neuroprotective effects and ability to modulate protein aggregation make it a promising candidate for managing these conditions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Bis(3,4-methylenedioxy)chalcone is utilized for its potential therapeutic applications in treating neurodegenerative diseases. Its unique chemical structure and bioactivity contribute to its potential as a lead compound in drug development for these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 76530-89-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,5,3 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 76530-89:
(7*7)+(6*6)+(5*5)+(4*3)+(3*0)+(2*8)+(1*9)=147
147 % 10 = 7
So 76530-89-7 is a valid CAS Registry Number.

InChI:InChI=1/C17H12O5/c18-13(12-3-6-15-17(8-12)22-10-20-15)4-1-11-2-5-14-16(7-11)21-9-19-14/h1-8H,9-10H2/b4-1+

76530-89-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	1,3-bis(1,3-benzodioxol-5-yl)prop-2-en-1-one

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76530-89-7 SDS

76530-89-7Upstream product

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76530-89-7Relevant academic research and scientific papers

Bi(OTf)3 catalyzed disproportionation reaction of cinnamyl alcohols

Chan, Chieh-Kai,Tsai, Yu-Lin,Chang, Meng-Yang

, p. 3368 - 3376 (2017/05/22)

Bi(OTf)3 catalyzed disproportionation reaction of cinnamyl alcohols provides chalcones and benzyl styrenes. The use of various metal triflates is investigated herein for facile and efficient redox transformation. A plausible mechanism has been proposed.

Synthesis and characterization of some chalcones and their cyclohexenone derivatives

Sreevidya, Thekke V.,Narayana, Badiadka,Yathirajan, Hemmige S.

experimental part, p. 174 - 181 (2010/11/21)

A series of chalcones and their derivatives have been synthesized. Chalcones, 1-(1,3-benzodioxol-5-yl)-3-(aryl)-prop-2-en-1-ones were prepared by the aldol condensation of 1-(1,3-benzodioxol-5-yl)ethanones and aryl aldehydes. Based-catalyzed condensation

A simple and scalable procedure for TiCl4-promoted aldol reaction

Su, Qiaogong,Wood, Jeffery L.

experimental part, p. 4237 - 4239 (2010/09/07)

TiCl4-promoted aldol reaction was carried out by adding TiCl4 to a solution of the aldol reaction substrates and (i-Pr) 2NEt (DIPEA) in CH2Cl2. Compared to the conventional order of addition (sequentially adding TiCl4, DIPEA, and piperonal to the lactone 2 in CH2Cl2), this simplified procedure, gave a much cleaner reaction that could be executed on large scale and without cryogenic cooling. However this procedure provided no stereoselectivity.

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