Welcome to LookChem.com Sign In|Join Free
  • or
7-Quinolinecarboxylic acid, 2-[2-(3,4-dihydroxy-5-methoxyphenyl)ethenyl]-8-hydroxy- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

765304-52-7

Post Buying Request

765304-52-7 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

765304-52-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 765304-52-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,5,3,0 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 765304-52:
(8*7)+(7*6)+(6*5)+(5*3)+(4*0)+(3*4)+(2*5)+(1*2)=167
167 % 10 = 7
So 765304-52-7 is a valid CAS Registry Number.

765304-52-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name FZ-41

1.2 Other means of identification

Product number -
Other names FZ41

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:765304-52-7 SDS

765304-52-7Downstream Products

765304-52-7Relevant academic research and scientific papers

Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase

Sliman, Faten,Blairvacq, Mélina,Durieu, Emilie,Meijer, Laurent,Rodrigo, Jordi,Desma?le, Didier

scheme or table, p. 2801 - 2805 (2010/07/05)

Pim-1 kinase is a cytoplasmic serine/threonine kinase that controls programmed cell death by phosphorylating substrates that regulate both apotosis and cellular metabolism. A series of 2-styrylquinolines and quinoline-2-carboxamides has been identified as potent inhibitors of the Pim-1 kinase. The 8-hydroxy-quinoline 7-carboxylic acid moiety appeared to be a crucial pharmacophore for activity. Molecular modeling indicated that interaction of this scaffold with Asp186 and Lys67 residues within the ATP-binding pocket might be responsible for the kinase inhibitory potency.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 765304-52-7