76566-98-8Relevant academic research and scientific papers
Total Synthesis of Ionophore Antibiotic X-14547A
Nicolaou, K. C.,Papahatjis, D. P.,Claremon, D. A.,Magolda, R. L.,Dolle, R. E.
, p. 1440 - 1456 (2007/10/02)
A highly stereocontrolled and convergent total synthesis of optically active ionophore antibiotic X-14547A (1) was designed and carried out.Degradative reactions led to the key intermediates 3 and 6, which served as convenient comparison stages.The tetrah
Ionophore Antibiotic X-14547A. Degradation Studies and Stereoselective Construction of the "Right Wing" (C11-C25 Fragment) by an Intramolecular Diels-Alder Reaction
Nicolaou, Kyriacos C.,Magolda, Ronald L.
, p. 1506 - 1508 (2007/10/02)
Studies directed toward the total synthesis of the ionophore antibiotic X-14547A are reported.Degradation methods led to a number of "left-wing" fragments, whereas synthetic operations led to a "right- wing" fragment, in a highly efficient and stereoselec
