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2,5-DIBROMOBENZOTRIFLUORIDE, also known as 1,4-Dibromo-2-(trifluoromethyl)benzene, is an organic compound with the chemical formula C7H3Br2F3. It is characterized by the presence of two bromine atoms at the 2nd and 5th positions on a benzene ring, along with a trifluoromethyl group attached to the same ring. 2,5-DIBROMOBENZOTRIFLUORIDE exhibits unique chemical properties and reactivity, making it a versatile building block in various chemical synthesis processes.

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  • 7657-09-2 Structure
  • Basic information

    1. Product Name: 2,5-DIBROMOBENZOTRIFLUORIDE
    2. Synonyms: 1,4-DIBROMO-2-TRIFLUOROMETHYL-BENZENE;2,5-DIBROMOBENZOTRIFLUORIDE;2,5-DIBROMO-A,A,A-TRIFLUOROTOLUENE;2,5-DIBROMO-ALPHA,ALPHA,ALPHA-TRIFLUOROTOLUENE;2,5-Dibromo Trifluoromethylbenzene;1,4-Dibromo-2-(trifluoromethyl)benzene, 2,5-Dibromo-alpha,alpha,alpha-trifluorotoluene;1,4-Bibromo-2-(trifluoromethyl)benzene;2,5-Dibromobenzotrifluoride,98%
    3. CAS NO:7657-09-2
    4. Molecular Formula: C7H3Br2F3
    5. Molecular Weight: 303.9
    6. EINECS: 231-620-1
    7. Product Categories: Aryl;C7;Halogenated Hydrocarbons;Fluorine series
    8. Mol File: 7657-09-2.mol
  • Chemical Properties

    1. Melting Point: 49-51 °C(lit.)
    2. Boiling Point: 47 °C
    3. Flash Point: >230 °F
    4. Appearance: /
    5. Density: 1.956 g/cm3
    6. Vapor Pressure: 0.282mmHg at 25°C
    7. Refractive Index: 1.512
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: soluble in Methanol
    10. BRN: 2261093
    11. CAS DataBase Reference: 2,5-DIBROMOBENZOTRIFLUORIDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2,5-DIBROMOBENZOTRIFLUORIDE(7657-09-2)
    13. EPA Substance Registry System: 2,5-DIBROMOBENZOTRIFLUORIDE(7657-09-2)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36/37/39
    4. RIDADR: 3276
    5. WGK Germany: 3
    6. RTECS:
    7. HazardClass: IRRITANT
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 7657-09-2(Hazardous Substances Data)

7657-09-2 Usage

Uses

Used in Pharmaceutical Industry:
2,5-DIBROMOBENZOTRIFLUORIDE is used as an intermediate in the synthesis of anti-cancer agents. Its unique structure allows for the development of novel compounds with potential therapeutic applications in cancer treatment.
Used in Polymer Industry:
2,5-DIBROMOBENZOTRIFLUORIDE is used as a novel anhydride compound to prepare polyamic acid and polyimide. These polymers are known for their high thermal stability, mechanical strength, and excellent chemical resistance, making them suitable for various high-performance applications, such as aerospace, electronics, and automotive industries.
Used in Organic Synthesis:
2,5-DIBROMOBENZOTRIFLUORIDE is used as a starting material to synthesize 4-bromo-2-(trifluoromethyl)benzaldehyde and functionalized alkynyl-substituted (trifluoromethyl)benzenes. These synthesized compounds can be further utilized in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 7657-09-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,5 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7657-09:
(6*7)+(5*6)+(4*5)+(3*7)+(2*0)+(1*9)=122
122 % 10 = 2
So 7657-09-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H3Br2F3/c8-4-1-2-6(9)5(3-4)7(10,11)12/h1-3H

7657-09-2 Well-known Company Product Price

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  • Alfa Aesar

  • (L03378)  2,5-Dibromobenzotrifluoride, 98%   

  • 7657-09-2

  • 5g

  • 780.0CNY

  • Detail
  • Alfa Aesar

  • (L03378)  2,5-Dibromobenzotrifluoride, 98%   

  • 7657-09-2

  • 25g

  • 3257.0CNY

  • Detail

7657-09-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-Dibromobenzotrifluoride

1.2 Other means of identification

Product number -
Other names Benzene, 1,4-dibromo-2-(trifluoromethyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7657-09-2 SDS

7657-09-2Relevant articles and documents

PROCESS FOR THE PREPARATION OF SUBSTITUTED BENZOTRIHALIDE

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Page/Page column 9, (2016/06/06)

The present invention provides a process for the preparation of compound of Formula I; wherein X is selected from the group consisting of fluorine, chlorine, bromine and iodine; Y is selected from X and -NR1R2; R1 and R1, independent of each other, are selected from the group consisting of hydrogen, C1-4 alkyl and –COR; R is C1-4 alkyl.

REACTIONS OF ORGANIC COMPOUNDS WITH SF4-HF-HALOGENATING AGENT SYSTEMS VI. REACTIONS OF BENZENE AND ITS DERIVATIVES WITH SF4-HF-Cl2(Br2)

Kunshenko, B. V.,Omarov, V. O.,Muratov, N. N.,Mikhailevskii, S. M.,Yagupol'skii, L. M.

, p. 108 - 112 (2007/10/02)

In the reactions of benzene-carboxylic and -dicarboxylic acids with SF4-HF-Cl2(Br2), apart from the conversion of carboxyls into trifluoromethyl groups, there occurs the halogenation of the benzene ring with the formation of the corresponding chloro- and bromo-containing (trifluoromethyl)- and bis(trifluoromethyl)-benzenes.

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