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Pyrrolo[1,2-a]quinoline-2-carboxylic acid ethyl ester, also known as PQCE, is a chemical compound characterized by a pyrroloquinoline core and an ethyl ester functional group. It is widely utilized in organic synthesis and medicinal chemistry as a key building block for the creation of biologically active molecules and pharmaceutical compounds. PQCE has garnered attention for its potential pharmacological properties, such as anti-cancer and anti-inflammatory activities, making it a significant asset in drug development and medicinal chemistry research.

76577-82-7

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76577-82-7 Usage

Uses

Used in Pharmaceutical Industry:
Pyrrolo[1,2-a]quinoline-2-carboxylic acid ethyl ester is used as a building block for the synthesis of various biologically active molecules and pharmaceutical compounds. Its unique structure and properties contribute to the development of new drugs with potential applications in treating a range of diseases.
Used in Medicinal Chemistry Research:
Pyrrolo[1,2-a]quinoline-2-carboxylic acid ethyl ester is used as a research tool for investigating its pharmacological properties, including anti-cancer and anti-inflammatory activities. This helps in understanding its potential as a therapeutic agent and in the design of novel drug candidates.
Used in Organic Synthesis:
Pyrrolo[1,2-a]quinoline-2-carboxylic acid ethyl ester is used as a key intermediate in the synthesis of complex organic molecules. Its versatile structure allows for the formation of a variety of derivatives, making it a valuable component in the creation of new chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 76577-82-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,5,7 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 76577-82:
(7*7)+(6*6)+(5*5)+(4*7)+(3*7)+(2*8)+(1*2)=177
177 % 10 = 7
So 76577-82-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO2/c1-2-18-15(17)12-9-13-8-7-11-5-3-4-6-14(11)16(13)10-12/h3-10H,2H2,1H3

76577-82-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl pyrrolo[1,2-a]quinoline-2-carboxylate

1.2 Other means of identification

Product number -
Other names ethyl pyrrolo<1,2-a>quinoline-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76577-82-7 SDS

76577-82-7Downstream Products

76577-82-7Relevant academic research and scientific papers

A mild preparation of substituted indolizines and indole from simple aromatic precursors using (trimethylsilyl)diazomethane

Zhu, Liusheng,Vimolratana, Marc,Brown, Sean P.,Medina, Julio C.

, p. 1768 - 1770 (2008/09/18)

A mild and convenient synthesis of substituted indolizines from readily available 2-(pyridin-2-yl)acetyl derivatives using (trimethylsilyl)diazomethane is described. The extension of this methodology to the synthesis of indole from 2-aminobenzaldehyde is also reported.

Synthesis and oral antiallergic activity of carboxylic acids derived from imidazo[2,1-c][1,4]benzoxazines, imidazo[1,2-a]quinolines, imidazo[1,2-a]quinoxalines, imidazo[1,2-a]quinoxalinones, pyrrolo[1,2-a]quinoxalinones, pyrrolo[2,3-a]quinoxalinones, and

Ager,Barnes,Danswan,Hairsine,Kay,Kennewell,Matharu,Miller,Robson,Rowlands,Tully,Westwood

, p. 1098 - 1115 (2007/10/02)

4H-Imidazo[2,1-c][1,4]benzoxazine-1-carboxylic acid (3) was found to possess potent activity in the IgE-induced rat passive cutaneous anaphylaxis model which may be predictive of clinical antiallergic activity. Compared to disodium cromoglycate (DSCG,1),

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