7659-36-1Relevant articles and documents
Simultaneous measurement of fluorescence, conversion and physical/mechanical properties for monitoring bulk and localized photopolymerization reactions in heterogeneous systems
Medel,Bosch,Grabchev,Shah,Liu,Aguirre-Soto,Stansbury
, p. 41275 - 41286 (2016)
An FT-NIR spectrometer, rheometer and fluorescence spectrophotometer were coupled for the real-time monitoring of polymerization reactions, allowing the simultaneous tracking of polymerization kinetics, storage modulus as well as fluorescence. In this study, a methacrylate functionalized dansyl chromophore (DANSMA) was synthesized and two different nanogels were made from urethane dimethacrylate and isobornyl methacrylate. Two series of resin formulations were prepared using the DANSMA probe, ethoxylated bisphenol A dimethacrylate as the matrix monomer, Irgacure 651 as the initiator and the dispersed, monomer-swollen nanogels to give clear UV-curable resins. Placement of the fluorescent probe either throughout the resin or linked into the nanogel before its dispersion in the matrix provides a tool to study how the nanogel structure affects local network development by means of fluorescence from the DANSMA probe. We demonstrate the potential of this new technique using a composite as the two phase system (resin and polymerizable nanogel) including a dansyl derivative as a polymerizable probe to follow the reactions that are taking places in both phases.
Antibacterial agent for shampoo and preparation method thereof
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Paragraph 0041; 0045; 0049; 0053; 0057; 0061, (2020/12/31)
The invention discloses an antibacterial agent for shampoo and a preparation method thereof. The preparation method comprises the following steps: reacting carboxymethyl chitosan and a silicone oil base solution under the action of dicyclohexylcarbodiimide and 4-dimethylaminopyridine, so that carboxyl of the carboxymethyl chitosan reacts with amino at one end of a molecular chain of the silicone oil base solution, and carboxymethyl chitosan molecules are connected with silicone oil base solution molecules and further react with an aminoethyl methacrylate quaternary ammonium salt; and reactinghydrogen on the molecular chain of the silicone oil base solution with double bonds of the aminoethyl methacrylate quaternary ammonium salt, so that aminoethyl methacrylate quaternary ammonium salt molecules are fixed on the molecular chain of the silicone oil base solution and further react with an intermediate 6, and amino on the intermediate 6 is condensed with partial carboxyl of the carboxymethyl chitosan, and as a result, the antibacterial agent is prepared. The antibacterial agent has an excellent antibacterial effect and is capable of inhibiting generation of dandruff.
Phenylboronate-diol crosslinked glycopolymeric nanocarriers for insulin delivery at physiological pH
Guo, Qianqian,Wu, Zhongming,Zhang, Xinge,Sun, Lei,Li, Chaoxing
, p. 911 - 920 (2014/02/14)
Research into polymers with glucose-sensitivity in physiological conditions has expanded recently due to their therapeutic potential in diabetes. Herein, to explore the glucose-responsive properties of a new polymer under physiological conditions, we synthesized an amphiphilic block glycopolymer based on phenylboronic acid and a carbohydrate, which was named poly(d- gluconamidoethyl methacrylate-block-3-acrylamidophenylboronic acid) (p(AAPBA-b-GAMA)). Based on the cross-linking between the diol groups of the carbohydrates and phenylboronic acid, the glycopolymers self-assembled to form nanoparticles (NPs). The glucose-sensitivity was revealed by the swelling behavior of the NPs at different glucose concentrations and was found to be dependent on the glucose level. The morphology of the NPs revealed by transmission electron microscopy showed that the NPs were spherical in shape with good dispersity. The cell viability of the NPs investigated by MTT assay was more than 90%, indicating that the glycopolymers had good cytocompatibility. Insulin could be loaded onto the glycopolymer NPs with high efficiency (up to 10%), and insulin release increased with enhancement of the glucose level in the medium. Such a glucose-responsive glycopolymer is an excellent candidate that holds great potential in the treatment of diabetes.