765908-10-9Relevant academic research and scientific papers
General catalytic synthesis of highly enantiomerically enriched terminal aziridines from racemic epoxides
Kim, Sang Kyun,Jacobsen, Eric N.
, p. 3952 - 3954 (2004)
If life deals you a lemon ...: Low selectivity in the [Co(salen)]-catalyzed kinetic resolution of terminal epoxides with N-Boc sulfonamides is parlayed into an efficient one-pot synthesis of enantiopure amino alcohol derivatives. This provides the foundation for a general route to the title compounds (see scheme; Boc = tertbutoxycarbonyl; Ns = 2-nitrobenzenesulfonyl).
