765951-41-5

Upstream product

• 33603-90-6 (2Z)-2-bromo-3-phenyl-2-propenal 
• 155603-86-4 1-(N,N-dimethylsulfamoyl)-2-(tributylstannyl)imidazole 

Downstream Products

• 765951-42-6 2-((1RS)-1-benzyl-2-{[(tert-butyl)(dimethyl)silyl]oxy}ethyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide 
• 855780-71-1 5-benzyl-2-[(1RS)-1-benzyl-2-hydroxyethyl]-N,N-dimethyl-1H-imidazole-1-sulfonamide 
• 855780-72-2 S-((2RS)-2-{5-benzyl-1-[(dimethylamino)sulfonyl]-1H-imidazol-2-yl}-3-phenylpropyl) ethanethioate 
• 855780-70-0 5-benzyl-2-((1RS)-1-benzyl-2-{[(tert-butyl)(dimethyl)silyl]oxy}ethyl)-N,N-dimethyl-1H-imidazole-1-sulfonamide 
• 765951-43-7 2-(1-benzyl-2-{[(tert-butyl)(dimethyl)silyl]oxy}ethyl)-5-[hydroxy(phenyl)methyl]-N,N-dimethyl-1H-imidazole-1-sulfonamide 

Relevant academic research and scientific papers

A new class of inhibitors for the metalloprotease neprilysin based on a central imidazole scaffold

Neprilysin (NEP; neutral endopeptidase EC 3.4.24.11) is a Zn II-dependent, membrane-bound endopeptidase. NEP is widely distributed in the organs, particularly in the kidneys and lungs, and it is involved in the metabolism of a number of smaller