765959-00-0Relevant articles and documents
Synthesis of ortho-phenyl substituted MeO-BIPHEP ligand and its application in Rh-catalyzed asymmetric hydrogenation
Wu, Shulin,He, Minsheng,Zhang, Xumu
, p. 2177 - 2180 (2004)
A new BIPHEP-type ligand with phenyl groups at the 3,3′-positions, o-Ph-MeO-BIPHEP 3 was prepared. This ligand afforded excellent enantioselectivities when used in the Rh-catalyzed asymmetric hydrogenation of α-dehydroamino acid derivatives. The strong influence of o-phenyl groups of the ligand on the enantioselectivities of the reaction has been demonstrated by a comparison with its parent ligand MeO-BIPHEP.
Ph3P-mediated highly selective C(α)-P coupling of quinone monoacetals with R2P(O)H: Convenient and practical synthesis of: Ortho -phosphinyl phenols
Shen, Ruwei,Zhang, Ming,Xiao, Jing,Dong, Chao,Han, Li-Biao
, p. 5111 - 5116 (2018/11/24)
A highly selective Ph3P-mediated C(α)-P coupling reaction of quinone monoacetals with secondary phosphine oxides is developed to provide an effective method for the synthesis of a wide array of ortho-phosphinylphenols in good to excellent yields. This protocol can be adopted for scale-up synthesis directly from cheap and abundant phenols, and the products can be easily obtained in high yields by simple filtration without the use of organic extraction or chromatography.
