76605-65-7Relevant articles and documents
Synthesis of some photosensitizing methylangelicins, as monofunctional reagents for DNA
Guiotto,Rodighiero,Pastorini,et al.
, p. 489 - 494 (2007/10/02)
angelicins methylated angelicans were synthesized for obtaining monofunctional reagents for DNA; these compounds may present some interest with regard to the development of useful drugs in photochemotheapy. The new derivatives photobind covalently to DNA, however, they are unable to produce inter-strand, cross-linkages in the macromolecule. Thephotobiological activity was tested on phage T2 and was higher for the methylated derivatives than for angelicin.