76609-43-3

Upstream product

• 100-39-0 benzyl bromide 
• 19825-40-2 2,4-Dihydroxy-3-C-prenylacetophenone 
• 84575-17-7 (+/-)-8-acetyl-3,5-dihydroxy-2,2-dimethylchroman 
• 100-44-7 benzyl chloride 
• 76609-42-2 4-benzyloxy-3-prenylresacetophenone 

Downstream Products

• 124395-06-8 (+/-)-4'-benzyloxy-5''-hydroxy-6'',6''-dimethyldihydropyrano(2',3':2'',3'')chalcone 
• 76609-44-4 (+/-)-4'-benzyloxybavachromanol 
• 74061-77-1 4,4',5''-trihydroxy-6'',6''-dimethyldihydropyrano(2'',3'':2'.3')-chalcone 
• 124410-71-5 (+/-)-4',5''-dihydroxy-6'',6''-dimethyldihydropyrano(2',3':2'',3'')chalcone 

Relevant academic research and scientific papers

BAKUCHALCONE, A DIHYDROFURANOCHALCONE FROM THE SEEDS OF PSORALEA CORYLIFOLIA

A new dihydrofuranochalcone has been identified in seeds of Psoralea corylifolia and its structure confirmed by synthesis.Key Word Index - Psoralea corylifolia; Leguminosae; 4,2'-dihydroxy-2''-(1-hydroxy-1-methylethyl)-2'',3''-dihydrofurano(4'',5'':3',4')chalcone; (+/-)-6-acetyl-3,5-dihydroxy-2,2-dimethylchroman; (+/-)-8-acetyl-3,5-dihydroxy-2,2-dimethylchroman; (+/-)-5-acetyl-2,3-dihydro-2(1-hydroxy-1-methylethyl)-4-hydroxybenzofuran.

Syntheses of (+/-)-Bavachromanol and (+/-)-7-O-Methylpsoralenol

Total synthesis of (+/-)-bavachromanol (1) and partial synthesis of (+/-)-7-O-methylpsoralenol (2) are described.The key step in the synthesis of 1 is the conversion of 4-benzyloxy-3-prenylresacetophenone (II) to (+/-)-3-hydroxychroman (III) by treatment with m-chloroperbenzoic acid.Similarly, synthesis of 2 has been achieved in a single-step reaction of m-chloroperbenzoic acid with 7-O-methylneobavaisoflavone.