7661-14-5

Basic information

• Product Name: 3-bromo-N-(4-methoxyphenyl)propanamide
• Synonyms: 3-Bromo-N-(4-methoxyphenyl)propanamide; propanamide, 3-bromo-N-(4-methoxyphenyl)-
• CAS NO: 7661-14-5
• Molecular Formula: C₁₀H₁₂BrNO₂
• Molecular Weight: 258.1118
• Mol File: 7661-14-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 411.2°C at 760 mmHg
• Flash Point: 202.5°C
• Density: 1.464g/cm³
• Vapor Pressure: 5.69E-07mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 3-bromo-N-(4-methoxyphenyl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-N-(4-methoxyphenyl)propanamide(7661-14-5)
• EPA Substance Registry System: 3-bromo-N-(4-methoxyphenyl)propanamide(7661-14-5)

Safety Data

• Hazardous Substances Data: 7661-14-5(Hazardous Substances Data)

Upstream product

• 590-92-1 3-Bromopropionic acid 
• 104-94-9 4-methoxy-aniline 
• 15486-96-1 3-Bromopropionyl chloride 

Downstream Products

• 3835-21-0 6-methoxy-2,3-dihydroquinolin-4(1H)-one 
• 1235866-21-3 9-O-[(3-oxo-3-p-methoxyphenylamino)propyl]berberine bromide 
• 191168-84-0 N-(4-Methoxy-phenyl)-3-piperazin-1-yl-propionamide 
• 879216-10-1 3-azido-N-(4-methoxy-phenyl)-propionamide 
• 127756-67-6 4-benzoyloxy-1-(4-methoxyphenyl)azetidin-2-one 
• 127756-71-2 4-(2-bromoethoxy)-1-(4-methoxyphenyl)azetidin-2-one 
• 127756-72-3 4-acetoxy-1-(4-methoxyphenyl)azetidin-2-one 
• 3954-50-5 6-methoxy-1-methyl-2,3-dihydro-1H-quinolin-4-one 
• 1393743-06-0 N-hydroxy-4-{[(4-methoxy-phenylcarbamoyl-ethyl)-amino]methyl}benzamide 

Relevant articles and documents

Synthesis and structure-activity relationships of (–)-cis-N-normetazocine-based LP1 derivatives

(–)-cis-N-Normetazocine represents a rigid scaffold able to mimic the tyramine moiety of endogenous opioid peptides, and the introduction of different N-substituents influences affinity and efficacy of respective ligands at MOR (mu opioid receptor), DOR (

Formation of acridones by ethylene extrusion in the reaction of arynes with β-lactams and dihydroquinolinones

N-Unsubstituted β-lactams react with a molecule of aryne by insertion into the amide bond to form a 2,3-dihydroquinolin-4-one, which subsequently reacts with another molecule of aryne to form an acridone by extrusion of a molecule of ethylene. 2,3-Dihydroquinolin-4-ones react under the same reaction conditions to afford identical results. This is the first example of ethylene extrusion in aryne chemistry.

Design, synthesis and biological evaluation of hydroxamic acid derivatives as potential high density lipoprotein (HDL) receptor CLA-1 up-regulating agents

Trichostatin A (TSA) and suberoylanilide hydroxamic acid (SAHA) were reported in our recent publication as novel human high density lipoprotein (HDL) receptor CD36 and Lysosomal integral membrane protein-II Analogous-1 (CLA-1) up-regulators. As part of a