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N-acetyl-DL-pentafluorophenylalanine is a synthetic chemical compound that features a unique structure, combining an N-acetyl group with a pentafluorophenylalanine moiety. N-acetyl-DL-pentafluorophenylalanine is characterized by the presence of five fluorine atoms attached to a phenyl ring, which is connected to an alanine amino acid through an amide linkage. The fluorination of the phenyl ring significantly influences the compound's electronic properties, potentially enhancing its reactivity or stability. N-acetyl-DL-pentafluorophenylalanine is of interest in various fields, including medicinal chemistry, where it may be used as a building block for the synthesis of more complex molecules or as a probe to study the effects of fluorination on biological activity. Its properties, such as increased lipophilicity and potential for hydrogen bonding, make it a valuable tool in the design of new drugs and materials.

7662-75-1

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7662-75-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7662-75-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,6 and 2 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7662-75:
(6*7)+(5*6)+(4*6)+(3*2)+(2*7)+(1*5)=121
121 % 10 = 1
So 7662-75-1 is a valid CAS Registry Number.

7662-75-1Downstream Products

7662-75-1Relevant academic research and scientific papers

The Enantioselective Dakin-West Reaction

Wende, Raffael C.,Seitz, Alexander,Niedek, Dominik,Schuler, S?ren M. M.,Hofmann, Christine,Becker, Jonathan,Schreiner, Peter R.

, p. 2719 - 2723 (2016/02/27)

Here we report the development of the first enantioselective Dakin-West reaction, yielding α-acetamido methylketones with up to 58 % ee with good yields. Two of the obtained products were recrystallized once to achieve up to 84 % ee. The employed methylimidazole-containing oligopeptides catalyze both the acetylation of the azlactone intermediate and the terminal enantioselective decarboxylative protonation. We propose a dispersion-controlled reaction path that determines the asymmetric reprotonation of the intermediate enolate after the decarboxylation.

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