76630-75-6

Upstream product

• 38634-12-7 6-methyl-3-phenyl-1,2,4,5-tetrazine 
• 5333-86-8 ethyl benzimidate hydrochloride 

Downstream Products

• 1163682-19-6 N-(p-nitrophenyl)-6-methyl-3-phenyl-1,6-dihydro-1,2,4,5-tetrazine-1-carboxamide 
• 1163682-16-3 N-(p-methylphenyl)-6-methyl-3-phenyl-1,6-dihydro-1,2,4,5-tetrazine-1-carboxamide 
• 1163682-18-5 N-(p-methoxyphenyl)-6-methyl-3-phenyl-1,6-dihydro-1,2,4,5-tetrazine-1-carboxamide 
• 1163682-30-1 benzyl 6-methyl-3-phenyl-1,6-dihydro-1,2,4,5-tetrazine-1-carboxylate 
• 1163682-35-6 1-acetyl-6-methyl-3-phenyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-28-6 1-methyl-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-25-3 1-(3-chlorobenzyl)-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-20-8 1-(2-methylbenzyl)-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-26-4 1-(4-chlorobenzyl)-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-27-5 1-allyl-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-22-0 1-(4-methylbenzyl)-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-29-7 1-ethyl-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 1283598-19-5 1-benzyl-3-phenyl-6-methyl-1,6-dihydro-1,2,4,5-tetrazine 
• 588-68-1 1,2-di(benzylidene)hydrazine 

Relevant academic research and scientific papers

Synthesis and X-ray crystallographic analysis of some 1,6-dihydro-1,2,4,5- tetrazines

Eight 1,6-dihydro-1,2,4,5-tetrazines (2a-2h) were synthesised by reaction of sodium borohydride with 3,6-substituted-1,2,4,5-tetrazines. The structure of 2c was confirmed by single-crystal X-ray diffraction. The central six-membered ring of 2c has an obvious unsymmetrical boat conformation. It could be considered that the molecule has a homoaromaticity.

1,6-Dihydro-1,2,4,5-tetrazine, a Neutral Homoaromatic System

1H NMR spectroscopy of some 1,6-dihydro-3-aryl(alkyl)-1,2,4,5-tetrazines and their conjugate bases and acids, at various temperatures, shows that these species are all homoaromatic.The hydrogens at position 6 have a different orientation toward the aromatic ring; one is oriented above and the other away from the aromatic ring, thus resulting in a large difference in chemical shift.The various parameters (ΔH(excit.), ΔS(excit.), and ΔG(excit.)) are determined by dynamic NMR measurements.