76645-81-3Relevant academic research and scientific papers
Synthesis of Bis(phosphinomethyl)amines via Bis(hydroxymethyl)phosphonium Salts. Isolation of 9,9-Bis(hydroxymethyl)-9-phosphoniabicyclononane Hydrogensulfate and Chloride Salts, and the Crystal Structures of (1+)Cl(1-) and <(C6H11)2P
Fawcett, John,Hoye, Peter A. T.,Kemmitt, Raymond D. W.,Law, David J.,Russell, David R.
, p. 2563 - 2568 (2007/10/02)
Phosphines of the type PR2H reacted readily with formaldehyde in the presence of acid to afford high yields of bis(hydroxymethyl)phosphonium salts (1+)X(1-), (1+)X(1-), , and (X = Cl or HSO4).Treatment of the mixed
OPTISCH AKTIVE N-PHOSPHINOMETHYLIERTE α-AMINOSAEUREN: SYNTHESE UND ANWENDUNG ALS LIGANDEN IN ASYMMETRISCHEN HYDRIERUNGEN MIT RHODIUM-KOMPLEXEN
Kellner, K.,Tzschach, A.,Nagy-Magos, A.,Marko, L.
, p. 307 - 314 (2007/10/02)
α-Aminoacids, their esters and sodium salts may be transformed by a modified Mannich-reaction into N-phosphinomethyl or N,N-bis(phosphinomethyl) derivatives.The sodium or triethylammonium salts of the chiral bisphosphines L-(-)-N,N-bis(diphenylphosphinomethyl)-alanine and -valine may be used as ligands to form enantioslective hydrogenation catalysts with rhodium complexes.The highest optical yield achieved was 29percent.
