76670-75-2

Upstream product

• 87160-97-2 DL-(1α,2β,3α,6α)-2-O-(Methylsulfonyl)-7-(4-methylphenylsulfonyl)-7-azabicyclo<4.1.0>hept-4-en-2,3-diol-3-acetat 
• 87160-95-0 DL-(1α,2β,3α,6β)-1,2-Bis-O-(methylsulfonyl)-6-<(4-methylphenylsulfonyl)amino>-4-cyclohexen-1,2,3-triol-3-acetat 
• 112346-61-9 DL-(1α,2α,3β,6β)-2-Brom-6-<(4-methylphenylsulfonyl)amino>-4-cyclohexen-1,3-diol 
• 76670-80-9 DL-(1α,2α,3β,6α)-3-<(4-Methylphenylsulfonyl)amino>-7-oxabicyclo<4.1.0>hept-4-en-2-ol 
• 69945-44-4 (1RS,2SR,3RS,4RS)-2,3-dibromocyclohex-5-ene-1,4-diol 
• 69945-45-5 (+/-)-(3/4,5,6)-4-bromo-5,6-epoxy-3-hydroxycyclohexene 
• 127-65-1 chloroamine-T 
• 87160-88-1 DL-(1α,2α,5α,6α)-5-<(4-Methylphenylsulfonyl)amino>-7-oxabicyclo<4.1.0>hept-3-en-2-ol 
• 76670-78-5 N-((1S,4R,5S,6R)-5-Bromo-4,6-dihydroxy-cyclohex-2-enyl)-4-methyl-benzenesulfonamide 
• 140696-30-6 (1R,2S,3R,6R)-2-bromo-7-oxabicyclo[4.1.0]hept-4-en-3-ol 
• 76670-80-9 N-((1S,2R,3S,6R)-2-Hydroxy-7-oxa-bicyclo[4.1.0]hept-4-en-3-yl)-4-methyl-benzenesulfonamide 
• 87160-94-9 DL-(1α,2β,3α,6β)-6-<(4-Methylphenylsulfonyl)amino>-4-cyclohexen-1,2,3-triol-3-acetat 

Downstream Products

• 76670-76-3 4-(4-Methylphenylsulfonyl)-4H-1,4-oxazocin 
• 87160-99-4 N-((1S,2R,3S,6R)-3-Methoxy-7-oxa-bicyclo[4.1.0]hept-4-en-2-yl)-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

cis,trans-Oxaaza-bis-?-homobenzenes - 4H-1,4-Oxazocines

The cis-oxaaza-bis-?-homobenzene framework has been synthesised via two routes starting from readily accessible materials (11, 25).As expected the N-SO2R derivatives 3a,b are sufficiently stable to be isolated; on heating, they readily and quantitatively undergo ?2 + ?2 + ?2>-cycloreversion to the 4H-1,4-oxazocines 6a,b (3b: t1/2(60 deg C) = 33.2 min; ΔG* = 104.0 kJ*mol-1).The latter prefer a non-planar, folded conformation.Using a precursor of 3b (27a), the thermally stable trans-oxaaza-bis-?-homobenzene 9 was obtained in very small yield (2 - 6percent) by two alternative pathways.

cis-Oxa,aza-σ-homobenzenes. Syntheses,[2+2+2]-cycloreversion reactions

cis-Dioxa,aza-tris-(8) and cis-oxa, aza-bis-σ-homobenzenes (21) have been synthesised. With activation barriers, which clearly support the concerted mechanism, they undergo [2+2+2]-cycloreversion yielding 7H-1,4,7-dioxazonines (9) and 4H-1,4-oxazocines (22), resp.