76671-16-4

Upstream product

• 108-98-5 thiophenol 
• 76670-99-0 (2R,3R)-3-Acetoxy-2-bromo-butyric acid 
• 77363-75-8 (R)-3-((S)-1-Acetoxy-ethyl)-1-tert-butoxycarbonylmethyl-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 77363-72-5 2-[((2R,3R)-3-Acetoxy-2-bromo-butyryl)-tert-butoxycarbonylmethyl-amino]-malonic acid diethyl ester 
• 77363-74-7 <3α(S^*),4α>-1-tert-butoxycarbonylmethyl-3-(1-acetoxyethyl)-4-ethoxycarbonyl-2-azetidinone-4-carboxylic acid 
• 77363-73-6 (R^*,S^*)-1-t-butoxycarbonylmethyl-3-(1-acetoxyethyl)-4,4-bis-(ethoxycarbonyl)-2-azetidinone 
• 77363-70-3 Acetic acid (1R,2R)-2-bromo-2-chlorocarbonyl-1-methyl-ethyl ester 
• 76671-03-9 (R)-3-((S)-1-Acetoxy-ethyl)-1-tert-butoxycarbonylmethyl-4-oxo-azetidine-2-carboxylic acid 
• 76671-16-4 [(R)-3-((S)-1-Acetoxy-ethyl)-2-oxo-4-(2-phenylsulfanyl-acetyl)-azetidin-1-yl]-acetic acid tert-butyl ester 
• 76671-16-4 <3α(S^*),4α>-1-tert-butoxycarbonylmethyl-3-(1-acetoxyethyl)-4-(1-oxo-2-phenylthioethyl)-2-azetidinone 
• 77363-71-4 N-bis(carboethoxy)methyl-N-tert-butoxycarbonyl-methylamine 
• 77363-72-5 (R^*,R^*)-N-bis(carboethoxy)methyl-N-tert-butoxycarbonylmethyl-2-bromo-3-acetoxybutylamide 
• 77363-75-8 <3α(S^*),4α>-1-tert-butoxycarbonylmethyl-4-ethoxycarbonyl-3-(1-acetoxyethyl)-2-azetidinone 
• 77363-70-3 (R^*,R^*)-2-bromo-3-acetoxybutyryl chloride 

Downstream Products

• 77363-82-7 <3α(S^*),4β>-1-tert-butoxycarbonylmethyl-3-(1-acetoxyethyl)-4-<1-oxo-2,2-bis(phenylthio)ethyl>-2-azetidinone 
• 76671-16-4 <3α(S^*),4β>-1-tert-butoxycarbonylmethyl-3-(1-acetoxyethyl)-4-(1-oxo-2-phenylthioethyl)-2-azetidinone 
• 86531-48-8 [(2R,3R)-3-((S)-1-Acetoxy-ethyl)-2-(1-hydroxy-2-phenylsulfanyl-ethyl)-4-oxo-azetidin-1-yl]-acetic acid tert-butyl ester 
• 77363-76-9 ((3R,4R)-3-((S)-1-Acetoxy-ethyl)-2-oxo-4-{(E)-2-[2-(trityl-amino)-ethylsulfanyl]-vinyl}-azetidin-1-yl)-acetic acid tert-butyl ester 
• 76671-17-5 [(2R,3R)-3-((S)-1-Acetoxy-ethyl)-2-(2-chloro-1-phenylsulfanyl-ethyl)-4-oxo-azetidin-1-yl]-acetic acid tert-butyl ester 
• 76671-18-6 [(2R,3R)-3-((S)-1-Acetoxy-ethyl)-2-(1-benzenesulfinyl-vinyl)-4-oxo-azetidin-1-yl]-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

A STEREOCONTROLLED FORMAL TOTAL SYNTHESIS OF (+/-)-THIENAMYCIN

The stereocontrolled synthesis of a key intermediate 20 for the preparation of (+/-)-thienamycin 1 is described.The key steps in the synthesis are the formation of the β-lactam ring by cyclization of the amide 5 via a complete SN2 mechanism, an