76678-30-3Relevant academic research and scientific papers
Grubbs cross-metathesis pathway for a scalable synthesis of γ-keto-α,β-unsaturated esters
Nair, Reji N.,Bannister, Thomas D.
, p. 1467 - 1472 (2014)
A direct and scalable route to γ-keto-α,β-unsaturated esters, useful intermediates in medicinal chemistry and natural products synthesis, is reported. The key step involves the use of Grubbs' second-generation olefin metathesis catalyst for cross-metathes
On the Preparation and Rearrangement of Some Vinylic Sulphoxides
Cass, Quezia B.,Jaxa-Chamiec, Albert A.,Kunec, Ellen K.,Sammes, Peter G.
, p. 2683 - 2686 (2007/10/02)
The condensation of methyl benzenesulphinylacetate 1 with a series of aldehydes has been explored using different catalysts.With zinc chloride, the enolate of 1 produces the conjugated ester directly.A base-catalysed rearrangement of these conjugated este
α-Amino Acids as Nucleophilic Acyl Equivalents, III. - Synthesis of (E)-3-Acylacrylic Esters and 4-Oxocarboxylic Esters
Wegmann, Helmut,Schulz, Guenter,Steglich, Wolfgang
, p. 1736 - 1743 (2007/10/02)
Base catalyzed addition of methyl propiolate to oxazolin-5-ones 1 yields mixtures of the diastereomeric methyl 3-(5-oxo-2-phenyl-2-oxazolin-4-yl)acrylates 2 which may be converted into (E)-3-acylacrylates 5 via hydrolytic ring opening to 3 and subsequent
