76686-84-5

Usage

Uses

Used in Pharmaceutical Industry:
3-(1H-1,2,4-TRIAZOL-1-YL)PROPANOIC ACID is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with antifungal and antimicrobial properties. Its presence in drug formulations can enhance their efficacy against a range of infections.
Used in Agrochemical Industry:
In the agrochemical sector, 3-(1H-1,2,4-TRIAZOL-1-YL)PROPANOIC ACID is utilized as a component in the creation of agrochemicals, where its antifungal and antimicrobial attributes are employed to protect crops from diseases and pests, thereby improving agricultural yields.
Used in Materials Science:
3-(1H-1,2,4-TRIAZOL-1-YL)PROPANOIC ACID is used as a building block in the field of materials science for its potential to contribute to the development of innovative polymers and coatings. Its unique chemical structure allows for the engineering of materials with enhanced properties, such as improved durability and resistance to environmental factors.
Overall, 3-(1H-1,2,4-TRIAZOL-1-YL)PROPANOIC ACID is a multifaceted chemical entity with a broad spectrum of applications that span from healthcare to agriculture and materials development, underscoring its importance as a valuable compound in modern scientific and industrial endeavors.

InChI:InChI=1/C5H7N3O2/c9-5(10)1-2-8-4-6-3-7-8/h3-4H,1-2H2,(H,9,10)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 79-10-7 acrylic acid 
• 24215-03-0 ethyl 3-(1H-1,2,4-triazol-1-yl)propanoate 

Relevant academic research and scientific papers

LIPOXYGENASE INHIBITORS

Various embodiments of the present disclosure are directed to compounds having Formula I, Formula II, Formula IIA, Formula III, Formula IIIA, Formula IIIB, and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases and/or treating associated diseases. In some embodiments, subject compounds are used to prepare a composition that is effective in treating neurodegenerative diseases.

Non-catalytic addition of 1,2,4-triazole to nucleophilic and electrophilic alkenes

Non-catalytic addition of 1,2,4-triazole to vinyl ethers and esters occurs on heating (65-175°C, 4-20 h) to give Markovnikov adducts (yield 30-100%). Electron-deficient alkenes (acrylonitrile, acrylic acid, 4-phenyl-3-buten-2-one) react with 1,2,4-triazole (78-190°C, 4-20 h) to give anti-Markovnikov adducts in yields of 45-83%.

6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter

2-Heterocyclyl-lower alkyl-6-hydroxy-lower alkyl-2-penem compounds of the formula STR1 in which R1 represents lower alkyl substituted by hydroxy or protected hydroxy, R2 represents carboxy or functionally modified carboxy, R3/s

Certain 1-hydroxyethane, 1,1-di-phosphonic acid derivatives useful in treating calcium metabolism disturbances

The present invention provides diphosphonates of the general formula: STR1 wherein Het is an imidazole, oxazole, isoxazole, thiazole, pyridine, 1,2,3-triazole, 1,2,4-triazole or benzimidazole radical, which is optionally substituted by alkyl, alkoxy, halogen, hydroxyl, carboxyl, an amino group optionally substituted by alkyl or alkanoyl radicals or a benzyl radical optionally substituted by alkyl, nitro, amino or aminoalkyl, A is a straight-chained or branched, saturated or unsaturated hydrocarbon chain containing 2 to 8 carbon atoms, X is a hydrogen atom, optionally substituted by alkanoyl, or an amino group optionally substituted by alkyl or alkanoyl radicals and R is a hydrogen atom or an alkyl radical; and the pharmacologically acceptable salts thereof. The present invention also provides processes for the preparation of these diphosphonates and pharmaceutical compositions containing them.