7669-84-3

Usage

Uses

Used in Pharmaceutical Industry:
H-CYS(BZL)-GLY-OH is used as a building block for the synthesis of therapeutic peptides and proteins. Its unique structure allows for the development of drugs with specific functions and properties.
Used in Biochemistry Research:
H-CYS(BZL)-GLY-OH is used as a research tool to study protein synthesis, folding, and interactions. Its presence in peptides can provide insights into protein structure and function.
Used in Biotechnology Applications:
H-CYS(BZL)-GLY-OH is used as a component in the design of novel biomaterials and biosensors. Its properties can be harnessed to create materials with specific biological activities or sensing capabilities.

Upstream product

• 7729-20-6 L-cystinyl-bis-glycine 
• 55559-23-4 N-benzyloxycarbonyl-S-benzylcysteinyl-glycine 
• 22911-82-6 S-benzilic-L-cysteic-NCA 
• 56-40-6 glycine 
• 2601-46-9 Z-L-Cys(Bzl)-Gly-OBzl 
• 100-44-7 benzyl chloride 
• 19246-18-5 cysteinylglycine 
• 3257-18-9 benzyloxycarbonyl-S-benzylcysteine 
• 3695-79-2 Z-(Bzl)-L-Cys-Gly-OEt 

Downstream Products

• 100135-16-8 (R)-3-(benzylmercapto-methyl)-piperazine-2,5-dione 
• 67101-54-6 N-(S-benzyl-L-cysteinyl)-glycine methyl ester 
• 15401-16-8 N-[S-benzyl-N-(N-benzyloxycarbonyl-L-γ-glutamyl)-L-cysteinyl]-glycine 
• 70-18-8 GLUTATHIONE 
• 90281-65-5 N-(S-benzyl-L-cysteinyl)-glycine benzyl ester 

Relevant academic research and scientific papers

Initial intraorgan formation of mercapturic acid

The disposition of S-benzyl-glutathione (BSG) in male Wistar rats was evaluated by the HPLC method to examine whether the kidney and liver contributed independently to the biosynthesis of S-benzyl-N-acetylcysteine (BNAc), a mercapturic acid (Chart 1). After intravenous injection, BSG was rapidly transported in both the kidney and the liver at a ratio of about 7:3. Simultaneously, a large amount of BNAc was found in both the kidney and the liver. In the kidney, S-benzyl-cysteine (BCys) reached a maximum concentration (Cmax) at 2 min after BSG injection, whereas BNAc reached Cmax within 3 to 5 min. The generation of BNAc was also observed in the liver. While renal BNAc reached Cmax within 3 to 5 min, hepatic BNAc reached Cmax around 5 min after BSG injection. Moreover, the elimination half-life of the BNAc after intravenous injection of the BSG was equivalent to that observed after intravenous injection of the BNAc itself. These results demonstrate that the kidney contributes to the initial intraorgan generation of BNAc and that this mercapturic acid is also synthesized in the liver and preferentially excreted into urine.

Preparation of peptides and cephalosporins

An improved process for producing a peptide and a cephalosporin which comprises treating a phosphoramide derivative of the formula: STR1 wherein R1 and R2 are each an alkyl group, a cycloalkyl group, an aryl group or an aralkyl group